Sarao Manbeer S., Blair Kyle
Griffin Hospital
Retina Consultants, Ltd
Adie syndrome, also known as Holmes–Adie syndrome, is named after William John Adie, a British neurologist of Australian descent, and Sir Gordon Morgan Holmes, an Irish neurologist. Both independently reported the condition in 1931, with Adie naming it Pseudo-Argyll Robertson pupil. Earlier, in 1881, Hughlings Jackson described mydriasis with pupillary paralysis. In 1906, Markus first characterized the tonic pupil. In 1914, Oloff demonstrated that tonic pupils could result from causes other than syphilis. Adie syndrome is a relatively common neurological disorder of uncertain etiology, characterized by unilateral or bilateral tonic pupillary dilation with light–near dissociation and tendon areflexia. Symptoms arise from autonomic disturbances that affect vasomotor and sudomotor functions. The disorder demonstrates a female predominance and is associated with absent or reduced deep tendon reflexes (DTRs). Progressive miosis, bilateral involvement (approximately 4% per year), and continued loss of DTRs are frequently observed. When associated with hypohidrosis, the condition defines the variant known as Ross syndrome.
艾迪综合征，也称为霍姆斯 - 艾迪综合征，以澳大利亚裔英国神经学家威廉·约翰·艾迪和爱尔兰神经学家戈登·摩根·霍姆斯爵士的名字命名。他们在1931年都报告了这种病症，艾迪将其命名为假性阿盖尔 - 罗伯逊瞳孔。早在1881年，休林斯·杰克逊就描述了伴有瞳孔麻痹的瞳孔散大，而在1906年，马库斯首次描述了强直性瞳孔。1914年，奥洛夫证明强直性瞳孔可能由梅毒以外的因素引起。艾迪综合征是一种病因不明的相对常见的神经系统疾病，包括单侧或双侧强直性扩张的瞳孔，伴有光近反射分离和腱反射消失。这些症状是由自主神经紊乱引起的，影响血管舒缩和发汗功能。女性患者居多，伴有深部腱反射减弱或消失。患者往往会出现进行性瞳孔缩小、双侧受累（每年4%）以及深部腱反射逐渐丧失。它可能与少汗症有关，在这种情况下，被称为罗斯综合征。
