对GAL4的缺失分析确定了两个转录激活区段。
Deletion analysis of GAL4 defines two transcriptional activating segments.
作者信息
Ma J, Ptashne M
出版信息
Cell. 1987 Mar 13;48(5):847-53. doi: 10.1016/0092-8674(87)90081-x.
PMID:3028647
Abstract
We describe the activities of a wide array of deletion mutants of GAL4, a yeast transcriptional activator. We identify two short regions of GAL4, each of which activates transcription when fused to the DNA-binding region of the molecule. Very large portions of GAL4 are not required for gene activation.
摘要
我们描述了酵母转录激活因子GAL4的一系列缺失突变体的活性。我们鉴定出GAL4的两个短区域，当它们与该分子的DNA结合区域融合时，每个区域都能激活转录。基因激活并不需要GAL4的很大一部分。
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