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我们能治愈鼻息肉吗?

Will we ever cure nasal polyps?

作者信息

Ta N H

机构信息

Norfolk and Norwich University Hospital, Norwich Medical School, University of East Anglia , Norwich , UK.

出版信息

Ann R Coll Surg Engl. 2019 Jan;101(1):35-39. doi: 10.1308/rcsann.2018.0149. Epub 2018 Oct 5.

DOI:10.1308/rcsann.2018.0149
PMID:30286644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6303820/
Abstract

BACKGROUND

Nasal polyposis is a benign hyperplastic growth of nasal mucosa. There is a paucity of evidence on the prevalence and incidence of nasal polyposis. Although nasal polyps can be asymptomatic, they can cause a spectrum of nasal problems including nasal obstruction, rhinorrhoea, nasal congestion, anosmia resulting in ageusia. Nasal polyps are mostly associated with chronic rhinosinusitis, The current management of chronic rhinosinusitis with nasal polyps is controversial and is not curative.

METHODS

A Medline search was conducted, using the keywords 'rhinosinusitis', 'sinusitis', 'classification' and ''aetiology.

FINDINGS

The current treatment of nasal polyposis in chronic rhinosinusitis with nasal polyps is still challenging. Emerging research through endotypes profiling aims to better understand the complexities of this heterogeneous disease to personalise treatment and provide a cure. Randomised controlled trials aim to provide robust evidence for current management options.

摘要

背景

鼻息肉是鼻黏膜的一种良性增生性病变。关于鼻息肉的患病率和发病率,证据较少。虽然鼻息肉可能无症状,但它们会引发一系列鼻部问题,包括鼻塞、流涕、鼻充血、嗅觉丧失进而导致味觉丧失。鼻息肉大多与慢性鼻窦炎相关,目前对于伴有鼻息肉的慢性鼻窦炎的治疗存在争议,且无法治愈。

方法

使用关键词“鼻窦炎”“鼻窦炎”“分类”和“病因”进行了医学文献数据库检索。

结果

目前对伴有鼻息肉的慢性鼻窦炎中鼻息肉的治疗仍然具有挑战性。通过内型分析的新兴研究旨在更好地理解这种异质性疾病的复杂性,以实现个性化治疗并提供治愈方法。随机对照试验旨在为当前的治疗选择提供有力证据。

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