Thomas Mike, Yawn Barbara P, Price David, Lund Valerie, Mullol Jocquim, Fokkens Wytske
Department of General Practice and Primary Care, University of Aberdeen, Aberdeen, Scotland, UK.
Prim Care Respir J. 2008 Jun;17(2):79-89. doi: 10.3132/pcrj.2008.00029.
This paper is a summary of the 2007 European Position Paper on Rhinosinusitis and Nasal Polyps (EP3OS)1 which was published in Rhinology in 2007. In order to widen dissemination of the EP3OS paper, the editors of Rhinology and the Primary Care Respiratory Journal (PCRJ) have agreed to publish this summary - which is focussed on the needs of general practitioners and community-based non-specialist clinicians - in the PCRJ. In the EP3OS process, an evidence-based methodology was used to identify evidence and to grade recommendations for clinical practice for the management of rhinosinusitis. The EP3OS Taskforce was commissioned by the European Academy of Allergology and Clinical Immunology (EAACI) with the aims of: * Presenting specialist and generalist clinicians with an updated summary of knowledge of rhinosinusitis and nasal polyposis * Providing clinicans with an evidence-based summary of diagnostic methods appropriate for specialist and generalist settings * Providing evidence-based recommendations for management in specialist and generalist settings * Proposing guidance for definitions and outcome measurements in clinical practice and in research in different settings. The current document aims to distil the information presented in the full EP3OS document1 into a shorter and more concise format suitable for use in primary care generalist settings. The summary recommendations for generalists are that clinicians should be aware that rhinitis and sinusitis usually co-exist, and that management strategies should encompass this. Acute rhinosinusitis is an inflammatory condition that may be diagnosed on the basis of acute symptoms of nasal blockage, obstruction, congestion with or without facial pain or reduced smell; many episodes are self-limiting, but where symptoms persist or increase after five days, topical nasal steroids may be considered, with addition of antibiotics in patients with more severe or increasing symptoms. Non-resolution in 14 days, or the presence of atypical symptoms, should prompt consideration of referral to specialist care. Chronic rhinosinusitis occurs when symptoms have been present for >12 weeks, and anterior rhinoscopy or more detailed endoscopy should be performed to identify polyps. Topical nasal corticosteroids, nasal douching, and use of antihistamines in allergic patients, may be used in patients without, or with less symptomatic, polyps; referral to specialist care is needed for patients whose symptoms do not respond or who have large polyps.
本文是2007年发表于《鼻科学》杂志的《2007年欧洲鼻窦炎和鼻息肉立场文件》(EP3OS)的总结。为了更广泛地传播EP3OS文件,《鼻科学》和《基层医疗呼吸杂志》(PCRJ)的编辑们同意在PCRJ上发表这篇总结——该总结聚焦于全科医生和社区非专科临床医生的需求。在EP3OS制定过程中,采用了循证方法来确定证据,并对鼻窦炎管理的临床实践建议进行分级。EP3OS工作组受欧洲变态反应和临床免疫学会(EAACI)委托,目标如下:
向专科和全科临床医生提供鼻窦炎和鼻息肉知识的最新总结。
为临床医生提供适用于专科和全科环境的诊断方法的循证总结。
为专科和全科环境中的管理提供循证建议。
为不同环境下临床实践和研究中的定义及结果测量提出指导。
本文件旨在将完整的EP3OS文件中的信息提炼成更简短、更简洁的格式,适用于基层医疗全科环境。针对全科医生的总结建议是,临床医生应意识到鼻炎和鼻窦炎通常并存,管理策略应涵盖这一点。急性鼻窦炎是一种炎症性疾病,可根据鼻塞、阻塞、充血等急性症状,伴有或不伴有面部疼痛或嗅觉减退来诊断;许多发作是自限性的,但如果症状在五天后持续或加重,可考虑使用局部鼻用类固醇,症状更严重或加重的患者可加用抗生素。14天未痊愈或出现非典型症状,应考虑转诊至专科治疗。慢性鼻窦炎是指症状持续超过12周,应进行前鼻镜检查或更详细的内镜检查以确定是否有息肉。对于无息肉或息肉症状较轻的患者,可使用局部鼻用皮质类固醇、鼻腔冲洗以及在过敏患者中使用抗组胺药;症状无反应或有大息肉的患者需要转诊至专科治疗。