Elder B L, Smith T F
Diagn Microbiol Infect Dis. 1987 Feb;6(2):125-9. doi: 10.1016/0732-8893(87)90096-4.
Use of Quik-Sep System II (QSII) ion-exchange chromatography increased the detection of CMV-directed immunoglobulin M (IgM) compared to the prototype Quik-Sep System (QSI) (27 of 87 [31%] IgM-positive versus 20 of 87 [24%]). However, an increase in the number of false-positive rheumatoid factor-containing sera was found (15/52 [29%] versus 8/52 [15%]). Total immunoglobulin G (IgG) and IgM concentrations were higher in the QSII eluates compared to those from QSI, although total IgM recovery did not exceed 36% in either system.
与原型Quik-Sep系统(QSI)相比,使用Quik-Sep系统II(QSII)离子交换色谱法提高了巨细胞病毒定向免疫球蛋白M(IgM)的检测率(87例中有27例[31%]IgM阳性,而87例中有20例[24%])。然而,发现含类风湿因子血清的假阳性数量有所增加(52例中有15例[29%],而52例中有8例[15%])。与QSI洗脱液相比,QSII洗脱液中的总免疫球蛋白G(IgG)和IgM浓度更高,尽管在这两种系统中,总IgM回收率均未超过36%。