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圆形不透明影是 HIV 感染患者肺孢子菌肺炎的表现。

Round opacity as a presentation of pneumocystis jirovecii pneumonia in an HIV-infected patient.

机构信息

Department of Internal Medicine, "Dr. José E. González" University Hospital of the School of Medicine of the Nuevo León Autonomous University, Monterrey, Mexico.

Department of Internal Medicine, "Dr. José E. González" University Hospital of the School of Medicine of the Nuevo León Autonomous University, Monterrey, Mexico.

出版信息

Am J Emerg Med. 2019 Jan;37(1):176.e3-176.e4. doi: 10.1016/j.ajem.2018.09.051. Epub 2018 Sep 30.

Abstract

We present the case of a human immunodeficiency virus (HIV)-infected patient who arrived at our emergency department with fever, headache and exertional dyspnea. Throughout their stay, a chest x-ray was taken and a rounded opacity in his left lung was observed. CT images showed same abnormality and also ground glass opacities were seen. Symptoms and images strongly suggested a pulmonary infection due to pneumocystis jirovecii, however a presence of a round lesion should always lead to neoplasia being suspected. We empirically started treatment based on trimethoprim and sulfamethoxazole. Once available, flexible bronchoscopy and bronchoalveolar lavage was performed and stained preparations from his respiratory specimens confirmed the diagnosis of pulmonary pneumocystis infection. Finally, after 4 days of antibiotic therapy, an important clinical improvement was documented; a new chest x-ray was performed and the previous rounded opacity was absent. This finding strongly suggested a case of round pneumonia.

摘要

我们报告了一例人类免疫缺陷病毒 (HIV) 感染患者,因发热、头痛和劳力性呼吸困难而到我院急诊科就诊。在整个住院期间,拍摄了一张胸片,观察到其左肺有一个圆形不透明影。CT 图像显示同样的异常,也可见磨玻璃样混浊。症状和影像学强烈提示为卡氏肺孢子虫引起的肺部感染,然而,圆形病变的存在总是应该怀疑为肿瘤。我们根据复方磺胺甲噁唑经验性开始治疗。一旦获得,进行了软性支气管镜检查和支气管肺泡灌洗,从其呼吸道标本的染色制剂证实了肺卡氏肺孢子虫感染的诊断。最后,在抗生素治疗 4 天后,记录到重要的临床改善;进行了新的胸部 X 射线检查,先前的圆形不透明影消失。这一发现强烈提示为圆形肺炎。

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