Suppr超能文献

[并非所有磨玻璃影病例都是新冠肺炎——耶氏肺孢子菌肺炎作为鉴别诊断]

[Not all cases of groundglas opacity are COVID-19 - Pneumocystis-jirovecii-pneumonia as a differential diagnosis].

作者信息

Schüßler Meike, Müller Frank, Rauschning Dominic

机构信息

Bundeswehrzentralkrankenhaus Koblenz, Abteilung I - Klinik für Innere Medizin.

出版信息

Dtsch Med Wochenschr. 2021 Apr;146(9):603-607. doi: 10.1055/a-1391-4403. Epub 2021 Apr 30.

Abstract

HISTORY AND CLINICAL FINDINGS

A 68-year-old male patient with psorias and a bullous pemphigoid as an underlying disease developed bilateral groundglass opacities on chest CT under longer-term, higher-dose immunosuppressive therapy with methylprednisolone with clinical symptoms of dry cough, progressive dyspnea and fever.

DIAGNOSIS AND THERAPY

After the exclusion of COVID-19, Pneumocystis jirovecii pneumonia (PCP) was detected and a corresponding high-dose therapy with trimethoprim-sulfamethoxazole was initiated promptly.

COURSE

Nonetheless, a complicated course with bacterial superinfection and pulmonary aspergillosis as well as ARDS developed.

DISCUSSION AND CONCLUSION

In contrast to COVID-19, the typical course, diagnosis and therapy of Pneumocystitis jirovecii pneumonia are discussed. It is particularly emphasized that not all ground glass infiltrates in the CT chest image can be traced back to a COVID-19, even in a pandemic situation. Possible differential diagnoses should always be considered and taken into account in the diagnosis.

摘要

病史及临床检查结果

一名68岁男性患者,患有银屑病和大疱性类天疱疮这一基础疾病,在接受长期、高剂量甲基强的松龙免疫抑制治疗期间,胸部CT出现双侧磨玻璃影,伴有干咳、进行性呼吸困难和发热等临床症状。

诊断与治疗

排除新型冠状病毒肺炎(COVID-19)后,检测出耶氏肺孢子菌肺炎(PCP),并立即开始相应的高剂量复方磺胺甲恶唑治疗。

病程

尽管如此,仍出现了复杂的病程,伴有细菌重叠感染、肺曲霉病以及急性呼吸窘迫综合征(ARDS)。

讨论与结论

与COVID-19不同,本文讨论了耶氏肺孢子菌肺炎的典型病程、诊断和治疗。特别强调,即使在大流行情况下,胸部CT图像中的并非所有磨玻璃影都可归因于COVID-19。在诊断中应始终考虑并顾及可能的鉴别诊断。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验