Simmler Charlotte, Chen Shao-Nong, Anderson Jeff, Lankin David C, Phansalkar Rasika, Krause Elizabeth, Dietz Birgit, Bolton Judy L, Nikolic Dejan, van Breemen Richard B, Pauli Guido F
UIC/NIH Center for Botanical Dietary Supplements Research, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois.
HerbalGram. 2016 Spring;109:60-64.
The concept of botanical integrity (BI), introduced previously in issue 106, involves the determination of identity, homogeneity, bioactivity, and safety of plant-derived materials designated for human consumption. It goes beyond previously established quality control principles. The inaugural article in this series described the three major domains of expertise that are required to assess BI (as noted in Figure 1): botanical examination (botany), phytochemical analysis (chemistry), and biological efficacy and safety assessments (bioactivity, which encompasses the fields of pharmacology and toxicology).
植物完整性(BI)的概念在第106期中已有介绍,它涉及对指定供人类食用的植物源材料的身份、同质性、生物活性和安全性的测定。它超越了先前确立的质量控制原则。本系列的开篇文章描述了评估BI所需的三个主要专业领域(如图1所示):植物学检查(植物学)、植物化学分析(化学)以及生物功效和安全性评估(生物活性,涵盖药理学和毒理学领域)。