Belackova Vendula, Salmon Allison M, Schatz Eberhard, Jauncey Marianne
Uniting Sydney Medically Supervised Injecting Centre (MSIC), Sydney, Australia.
Correlation network, Foundation De Regenboog Groep, Amsterdam, The Netherlands.
Hepatol Med Policy. 2018 Aug 22;3:9. doi: 10.1186/s41124-018-0035-6. eCollection 2018.
Prevalence of Hepatitis C Virus (HCV) among people who inject drugs (PWID) is high. Risky injecting behaviours have been found to decrease in drug consumption rooms (DCRs) and supervised injecting facilities (SIFs), yet HCV prevention and treatment in these settings have not been extensively explored.
To determine the range and scope of HCV prevention and treatment options in these services, we assessed DCR/SIF operational features, their clients' characteristics and the HCV-related services they provide. A comprehensive online survey was sent to the managers of the 91 DCRs/SIFs that were operating globally as of September 2016. A descriptive cross-country analysis of the main DCR/SIF characteristics was conducted and bivariate logistic models were used to assess factors associated with enhanced HCV service provision.
Forty-nine valid responses were retrieved from DCRs/SIFs in all countries where they were established at the time of the survey (Australia, Canada, Denmark, France, Germany, Luxembourg, Netherlands, Norway, Spain and Switzerland). Internationally, the operational capacities of DCRs/SIFs varied in terms of funding, location, size and staffing, but their clients all shared common features of vulnerability and marginalisation. Estimated HCV prevalence rates were around 60%. Among a range of health and social services and referrals to other programs, most DCRs/SIFs provided HCV testing onsite (65%) and/or offered liver monitoring or disease management (54%). HCV treatment onsite was offered or was planned to be offered by 21% of DCRs/SIFs. HCV testing onsite was associated with provision of other services addressing blood-borne diseases and HCV treatment was linked to the provision of OST. HCV disease management was associated with employing a nurse at a DCR/SIF and HCV treatment was associated with employing a medical doctor.
DCRs/SIFs offer easy-to-access HCV-related services for PWID. The availability of onsite medical professionals and provision of support and education to non-medical staff are key to enhanced provision of HCV-related services in DCRs/SIFs. Funding and support for HCV treatment at the community level, via low-threshold services such as DCRs/SIFs, are worthy of action.
注射吸毒者中丙型肝炎病毒(HCV)的感染率很高。据发现,在毒品消费室(DCR)和受监管注射设施(SIF)中,危险注射行为有所减少,但这些场所的HCV预防和治疗尚未得到广泛探索。
为了确定这些服务中HCV预防和治疗选项的范围和规模,我们评估了DCR/SIF的运营特征、其客户的特点以及它们提供的与HCV相关的服务。向截至2016年9月在全球运营的91个DCR/SIF的管理人员发送了一份全面的在线调查问卷。对DCR/SIF的主要特征进行了描述性跨国分析,并使用二元逻辑模型评估与加强HCV服务提供相关的因素。
在调查时设有DCR/SIF的所有国家(澳大利亚、加拿大、丹麦、法国、德国、卢森堡、荷兰、挪威、西班牙和瑞士)的DCR/SIF中,共收到49份有效回复。在国际上,DCR/SIF的运营能力在资金、地点、规模和人员配备方面各不相同,但它们的客户都有脆弱性和边缘化的共同特征。估计HCV感染率约为60%。在一系列健康和社会服务以及转介到其他项目中,大多数DCR/SIF在现场提供HCV检测(65%)和/或提供肝脏监测或疾病管理(54%)。21%的DCR/SIF提供或计划在现场提供HCV治疗。现场HCV检测与提供其他针对血源性疾病的服务相关,而HCV治疗与提供阿片类药物替代治疗(OST)相关。HCV疾病管理与在DCR/SIF雇佣一名护士相关,而HCV治疗与雇佣一名医生相关。
DCR/SIF为注射吸毒者提供了易于获得的与HCV相关的服务。现场配备医疗专业人员以及为非医疗人员提供支持和教育是加强DCR/SIF中与HCV相关服务提供的关键。通过DCR/SIF等低门槛服务在社区层面为HCV治疗提供资金和支持值得采取行动。