Kumagai Yu, Iwayama Tadateru, Arimoto Takanori, Kutsuzawa Daisuke, Hashimoto Naoaki, Tamura Harutoshi, Nishiyama Satoshi, Takahashi Hiroki, Shishido Tetsuro, Yamauchi Sou, Yamanaka Tamon, Miyamoto Takuya, Watanabe Tetsu, Kubota Isao, Watanabe Masafumi
Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, Yamagata, Japan.
Pacing Clin Electrophysiol. 2018 Dec;41(12):1635-1642. doi: 10.1111/pace.13521. Epub 2018 Oct 24.
The predictive value of left atrial volume (LAV) in atrial fibrillation (AF) is known, but the relationship of right atrial volume (RAV) and biatrial volume (BAV) with AF recurrence after pulmonary vein isolation (PVI) is not clear. Cardiac magnetic resonance (CMR) imaging allows us to more precisely quantify atrial volume. We investigated LAV, RAV, and BAV as predictors of AF recurrence following PVI in AF patients.
We assessed 100 AF patients (age = 59.8 ± 9.5 years, 74 males, 26 females) who underwent nonenhanced CMR before their first PVI. LAV and RAV were measured using CMR. All patients were in sinus rhythm during CMR. BAV was calculated as the sum of LAV and RAV. During the 8-month follow-up, AF recurrence occurred in 23 patients. LAV, RAV, and BAV were significantly greater in patients with AF recurrence than in those without (LAV, 103.7 ± 25.8 vs 81.8 ± 24.2 mL, P < 0.001; RAV, 109.4 ± 27.0 vs 82.2 ± 19.6 mL, P < 0.001; BAV, 213.1 ± 46.7 vs 164.1 ± 38.7 mL, P < 0.001). Multivariate logistic regression analysis revealed that increased LAV, RAV, and BAV were significantly correlated with AF recurrence. The area under the receiver operation characteristic curve for BAV showed the largest value compared to that of LAV or RAV alone.
LAV, RAV, and BAV were independent predictors of AF recurrence after PVI. Quantifying BAV may additionally improve prognostic stratification compared with LAV or RAV.
左心房容积(LAV)在心房颤动(AF)中的预测价值已为人所知,但右心房容积(RAV)和双心房容积(BAV)与肺静脉隔离(PVI)后房颤复发的关系尚不清楚。心脏磁共振(CMR)成像使我们能够更精确地量化心房容积。我们研究了LAV、RAV和BAV作为房颤患者PVI后房颤复发的预测指标。
我们评估了100例房颤患者(年龄=59.8±9.5岁,男性74例,女性26例),这些患者在首次PVI前接受了非增强CMR检查。使用CMR测量LAV和RAV。所有患者在CMR检查期间均处于窦性心律。BAV计算为LAV与RAV之和。在8个月的随访期间,23例患者出现房颤复发。房颤复发患者的LAV、RAV和BAV显著高于未复发患者(LAV,103.7±25.8 vs 81.8±24.2 mL,P<0.001;RAV,109.4±27.0 vs 82.2±19.6 mL,P<0.001;BAV,213.1±46.7 vs 164.1±38.7 mL,P<0.001)。多因素逻辑回归分析显示,LAV、RAV和BAV增加与房颤复发显著相关。与单独的LAV或RAV相比,BAV的受试者操作特征曲线下面积显示出最大值。
LAV、RAV和BAV是PVI后房颤复发的独立预测指标。与LAV或RAV相比,量化BAV可能会进一步改善预后分层。