Viikari J, Lehtonen A
Int J Clin Pharmacol Ther Toxicol. 1986 Dec;24(12):668-70.
Primrose oil (about 72% of fatty acids 18:2 omega 6 and 9% of 18:3 omega 6) was supplemented in addition to the used diet of 20 hyperlipidemic patients for 3 months in an open study. The dose of primrose oil was 2.4 ml, 4.8 ml and 7.2 ml during the first, second and third month, respectively. Primrose oil increased the proportion of gamma-linolenic acid in serum cholesteryl esters (1.81 vs. 2.13%, p less than 0.05), phospholipids (0.65 vs. 0.82%, p less than 0.01), triglycerides (0.70 vs. 0.99%, p less than 0.01) and free fatty acids (0.80 vs. 0.91%, NS). It did not, however, change serum cholesterol, HDL cholesterol or triglyceride mean values. Blood pressure mean values remained unchanged during the follow-up as well.
在一项开放性研究中，除了给予20名高脂血症患者常规饮食外，还补充了月见草油（约72%的脂肪酸为18:2 ω6，9%为18:3 ω6），为期3个月。月见草油的剂量在第1、2、3个月分别为2.4毫升、4.8毫升和7.2毫升。月见草油增加了血清胆固醇酯中γ-亚麻酸的比例（1.81%对2.13%，p<0.05）、磷脂（0.65%对0.82%，p<0.01）、甘油三酯（0.70%对0.99%，p<0.01）和游离脂肪酸（0.80%对0.91%，无统计学意义）。然而，它并未改变血清胆固醇、高密度脂蛋白胆固醇或甘油三酯的均值。随访期间血压均值也保持不变。
