Laureno Robert, Lamotte Guillaume, Mark Alexander S
Department of Neurology, Medstar Washington Hospital Center, Washington, DC, USA.
Department of Neurology, Medstar Georgetown University Hospital, 3800 Reservoir Road NW, Washington, DC, 20007, USA.
BMC Res Notes. 2018 Oct 5;11(1):707. doi: 10.1186/s13104-018-3816-5.
This study describes the MRI changes associated with pontine and extrapontine myelinolysis secondary to rapid correction of hyponatremia in dogs. The authors discuss the relevance of the results for theories of pathogenesis and for diagnosis of patients.
MRI changes associated with pontine and extrapontine myelinolysis first occur on diffusion-weighted imaging. As a generalization, gadolinium enhancement, flair image change and T weighted image abnormality appear sequentially.
本研究描述了犬低钠血症快速纠正后继发脑桥和脑桥外髓鞘溶解的MRI变化。作者讨论了这些结果对发病机制理论及患者诊断的相关性。
与脑桥和脑桥外髓鞘溶解相关的MRI变化首先出现在弥散加权成像上。一般来说,钆增强、液体衰减反转恢复序列(FLAIR)图像变化和T加权图像异常依次出现。