暴发性葡萄球菌感染。
Fulminant Staphylococcal Infections.
机构信息
Department of Pediatric Emergency, Hospices Civils de Lyon, Hôpital Femme Mère Enfant, F-69677, Bron, France.
CIRI, Centre International de Recherche en Infectiologie, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, École Normale Supérieure de Lyon, University of Lyon, F-69007, Lyon, France.
出版信息
Microbiol Spectr. 2018 Oct;6(5). doi: 10.1128/microbiolspec.GPP3-0036-2018.
Fulminant staphylococcal infection indicates an explosive, intense, and severe infection occurring in a patient whose previous condition and antecedent would never have caused any anticipation of life-threatening development. This includes necrotizing pneumonia, necrotizing fasciitis, and to some extent toxic shock syndrome and infective endocarditis. In the three former diseases, toxin production plays a major role whereas in the latter (fulminant presentation of infective endocarditis), association with any particular toxinic profile has never been demonstrated. This article reviews the clinical, pathophysiological, and therapeutic aspects of these diseases.
暴发性葡萄球菌感染表示一种爆发性、强烈和严重的感染，发生于此前状况和既往病史都不会让人预料到会有生命威胁的发展的患者。这包括坏死性肺炎、坏死性筋膜炎，在一定程度上还包括中毒性休克综合征和感染性心内膜炎。在前面三种疾病中，毒素产生起主要作用，而在后一种疾病（感染性心内膜炎的暴发性表现）中，从未证明与任何特定的毒素特征有关。本文综述了这些疾病的临床、病理生理和治疗方面。
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