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尖锐湿疣(生殖器疣)。流行病学视角。

Condylomata acuminata (genital warts). An epidemiologic view.

作者信息

Chuang T Y

出版信息

J Am Acad Dermatol. 1987 Feb;16(2 Pt 1):376-84. doi: 10.1016/s0190-9622(87)70053-x.

Abstract

The understanding of condylomata acuminata (genital warts) has been enhanced by the recent development of diagnostic methods. Forty-two types of human papillomavirus were identified up to 1985, and at least sixteen types were involved in genital warts. The incidence of genital warts is around 0.1% in the general population and more than 0.5% in young persons. The incidence is known to be increasing rapidly and exceeding the incidence of genital herpes. Females are more prone to be affected. The epidemiologic evidence supporting the relationship between genital warts and genital cancer is overwhelming. The evidence also speaks for a strong correlation between genital warts and verrucous carcinoma of the genitalia, bowenoid papulosis, and laryngeal papilloma. The person having genital warts may also have other cutaneous warts. This observation is compatible with the finding that types of human papillomavirus involved in other cutaneous warts were found in genital warts. In view of the never and easier ways of diagnosing nonconspicuous condyloma acuminatum and the potential for malignant transformation of condyloma acuminatum, it is strongly recommended that patients should be followed up periodically for early detection of neoplasia.

摘要

诊断方法的最新进展加深了人们对尖锐湿疣(生殖器疣)的认识。截至1985年,已鉴定出42种人乳头瘤病毒,其中至少16种与生殖器疣有关。生殖器疣在普通人群中的发病率约为0.1%,在年轻人中超过0.5%。已知其发病率正在迅速上升,超过了生殖器疱疹的发病率。女性更容易受到影响。支持生殖器疣与生殖器癌之间关系的流行病学证据极为充分。证据还表明生殖器疣与生殖器疣状癌、鲍温样丘疹病和喉乳头瘤之间存在密切关联。患有生殖器疣的人也可能有其他皮肤疣。这一观察结果与在生殖器疣中发现与其他皮肤疣相关的人乳头瘤病毒类型的发现相符。鉴于诊断不明显的尖锐湿疣的新方法越来越多且更简便,以及尖锐湿疣有恶变的可能性,强烈建议对患者进行定期随访,以便早期发现肿瘤形成。

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