Neurology and Stroke Center, Department of Clinical Research, University Hospital and University of Basel, Petersgraben 4, 4031, Basel, Switzerland.
Stroke Research Center, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
J Neurol. 2018 Dec;265(12):3022-3033. doi: 10.1007/s00415-018-9061-y. Epub 2018 Oct 6.
Since their market approval, direct oral anticoagulants (DOACs) are being increasingly used for stroke prevention in patients with atrial fibrillation. However, the management of DOAC-treated patients with stroke poses several challenges for physicians in everyday clinical practice, both in the acute setting and in long-term care. This has spurred extensive research activity in the field over the past few years, which we review here.
自市场批准以来，直接口服抗凝剂（DOAC）越来越多地用于预防房颤患者的中风。然而，在急性和长期护理中，DOAC 治疗的中风患者的管理对医生来说都是日常临床实践中的几个挑战。这促使过去几年在该领域开展了广泛的研究活动，我们在此对其进行了综述。
