University of Oxford, Oxford, United Kingdom.
Semin Pediatr Neurol. 2018 Oct;27:10-15. doi: 10.1016/j.spen.2018.03.002. Epub 2018 Jun 20.
Neurological conditions in children represent a significant proportion of the global burden of disease, since they contribute to premature mortality and years lived with disability. The burden of neurological conditions, as measured by the total disability adjusted live years has decreased significantly over the last 25 years (1990-2015), mainly due to the reduction in the mortality, as the years lived with disability has increased slightly. However, in some regions of the world, notably South Asia and sub-Saharan Africa, the burden remains high, driven by the high incidence of prematurity, neonatal encephalopathy and infections of the central nervous system.
儿童神经疾病在全球疾病负担中占很大比例,因为它们导致了过早死亡和残疾年数。过去 25 年(1990-2015 年),通过总残疾调整生命年来衡量的神经疾病负担显著下降,主要是由于死亡率下降,而残疾年数略有增加。然而,在世界上一些地区,特别是南亚和撒哈拉以南非洲,由于早产、新生儿脑病和中枢神经系统感染的高发,疾病负担仍然很高。