Bell Sean M, Lam David H, Kearney Kathleen, Hira Ravi S
Department of Medicine, University of Washington, 1959 Northeast Pacific Street, Seattle, WA 98195, USA.
Department of Medicine, University of Washington, 1959 Northeast Pacific Street, Seattle, WA 98195, USA; Division of Cardiology, University of Washington, 1959 Northeast Pacific Street, Seattle, WA 98195, USA.
Cardiol Clin. 2018 Aug;36(3):395-408. doi: 10.1016/j.ccl.2018.03.007.
Ventricular fibrillation is a life-threatening cardiac arrhythmia that leads to a loss of cardiac function and sudden cardiac death. In this review, we summarize therapeutic interventions and guidelines for providers managing patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation in prehospital and emergency settings. Additionally, we review invasive management, including urgent coronary angiography, extracorporeal membrane oxygenation, and novel strategies for managing refractory ventricular fibrillation arrest. Although the majority of patients with refractory VF do not respond to conventional therapy, recent trials of novel strategies demonstrate encouraging results.
心室颤动是一种危及生命的心律失常，可导致心功能丧失和心源性猝死。在本综述中，我们总结了在院前和急诊环境中，为处理院外心脏骤停和难治性心室颤动患者的医疗服务提供者提供的治疗干预措施和指南。此外，我们还回顾了侵入性治疗管理，包括紧急冠状动脉造影、体外膜肺氧合，以及处理难治性心室颤动骤停的新策略。尽管大多数难治性室颤患者对传统治疗无反应，但最近关于新策略的试验显示出令人鼓舞的结果。
