Panda Subrat, Das Ananya
Department of Obstetrics and Gynecology, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, Meghalaya, India.
J Midlife Health. 2018 Jul-Sep;9(3):113-116. doi: 10.4103/jmh.JMH_21_18.
Perimenopause and menopause is an integral part of every woman's life constituting about 30% of the Indian female population. Hypothyroidism is a condition that can mimic menopausal symptoms very often. Therefore, routine screening of thyroid function in the climacteric and menopausal period to determine subclinical thyroid disease can be recommended.
With this background, we conducted a prospective study in our institute, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, to evaluate the abnormal thyroid function tests in perimenopausal and postmenopausal women aged 40-80 years.
Subclinical hypothyroidism status increases from the age group of 40-70 years and hypothyroidism increases in slow frequency from 40 to 70 years after that there is plateauing. Interestingly, the frequency of hyperthyroidism remains same in all the age groups.
Looking at the increased risks of thyroid disorders with age, screening of thyroid disorders can be started at the age of 40 years with estimation of serum levels of TSH. This gives us the opportunity to treat both subclinical and clinical hypothyroidism and hyperthyroidism women.
围绝经期和绝经是每位女性生命中不可或缺的一部分,约占印度女性人口的30%。甲状腺功能减退症是一种常可模拟绝经症状的病症。因此,可建议在更年期和绝经期间常规筛查甲状腺功能,以确定亚临床甲状腺疾病。
在此背景下,我们在我们的研究所——东北英迪拉·甘地区域卫生与医学科学研究所开展了一项前瞻性研究,以评估40至80岁围绝经期和绝经后女性甲状腺功能检查异常情况。
亚临床甲状腺功能减退状态在40至70岁年龄组中增加,甲状腺功能减退在40至70岁期间缓慢增加,之后趋于平稳。有趣的是,甲状腺功能亢进的发生率在所有年龄组中保持不变。
鉴于甲状腺疾病风险随年龄增加,可从40岁开始通过检测血清促甲状腺激素水平筛查甲状腺疾病。这使我们有机会治疗亚临床和临床甲状腺功能减退及甲状腺功能亢进的女性。