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Editorial: Drug Repositioning: Current Advances and Future Perspectives.

作者信息

Nishimura Yuhei, Hara Hideaki

机构信息

Department of Integrative Pharmacology, Mie University Graduate School of Medicine, Tsu, Japan.

Molecular Pharmacology, Department of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.

出版信息

Front Pharmacol. 2018 Sep 20;9:1068. doi: 10.3389/fphar.2018.01068. eCollection 2018.

DOI:10.3389/fphar.2018.01068
PMID:30294274
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6158627/
Abstract
摘要

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本文引用的文献

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Docking-based inverse virtual screening: methods, applications, and challenges.基于对接的反向虚拟筛选：方法、应用及挑战
Biophys Rep. 2018;4(1):1-16. doi: 10.1007/s41048-017-0045-8. Epub 2018 Feb 1.
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Drug Repositioning of Proton Pump Inhibitors for Enhanced Efficacy and Safety of Cancer Chemotherapy.质子泵抑制剂的药物重新定位以提高癌症化疗的疗效和安全性
Front Pharmacol. 2017 Dec 12;8:911. doi: 10.3389/fphar.2017.00911. eCollection 2017.
3
Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions.药物靶点交流群：一个构建药物-靶点相互作用共识知识库的社区努力。
Cell Chem Biol. 2018 Feb 15;25(2):224-229.e2. doi: 10.1016/j.chembiol.2017.11.009. Epub 2017 Dec 21.
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The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.集成网络细胞特征图谱 NIH 计划库：人类细胞对扰动反应的系统水平编目。
Cell Syst. 2018 Jan 24;6(1):13-24. doi: 10.1016/j.cels.2017.11.001. Epub 2017 Nov 29.
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A Next Generation Connectivity Map: L1000 Platform and the First 1,000,000 Profiles.下一代连接图谱：L1000平台及首批100万个图谱
Cell. 2017 Nov 30;171(6):1437-1452.e17. doi: 10.1016/j.cell.2017.10.049.
6
Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data.LINCS 计划的细胞信号网络综合数据库数据门户：对多样化大规模细胞扰动反应数据的综合访问。
Nucleic Acids Res. 2018 Jan 4;46(D1):D558-D566. doi: 10.1093/nar/gkx1063.
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DrugBank 5.0: a major update to the DrugBank database for 2018.DrugBank 5.0：2018 年 DrugBank 数据库的重大更新。
Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037.
8
Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment.利用一种新颖的计算药物重定位方法（DrugPredict），快速鉴定出用于癌症治疗的有效药物候选物。
Oncogene. 2018 Jan 18;37(3):403-414. doi: 10.1038/onc.2017.328. Epub 2017 Oct 2.
9
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Oncotarget. 2017 Jun 16;8(35):58801-58808. doi: 10.18632/oncotarget.18522. eCollection 2017 Aug 29.
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The Drug Repurposing Hub: a next-generation drug library and information resource.药物再利用中心：一个新一代药物库及信息资源。
Nat Med. 2017 Apr 7;23(4):405-408. doi: 10.1038/nm.4306.