Venishetty Shantan, Bhat Rama, Rajagopal K V
Department of Medicine, Kasturba Hospital, Manipal, Karnataka, India.
Department of Radiodiagnosis, Kasturba Hospital, Manipal, Karnataka, India.
Indian J Endocrinol Metab. 2018 Sep-Oct;22(5):678-682. doi: 10.4103/ijem.IJEM_641_17.
The aim of this study was to correlate serum uric acid (SUA) levels and carotid intima-media thickness (CIMT) in patients with type 2 diabetes mellitus (DM).
This study was a cross-sectional observational study on 103 diabetic patients conducted from September 2015 to May 2017.
We screened 103 patients with type 2 DM between the ages of 30-65 years. SUA levels and the CIMT were measured. The patients were divided into quartiles based on uric acid level. The CIMT of the quartiles is compared and analyzed.
Chi-squared test, Analysis of Variance, and Pearson's correlation.
Uric acid levels were positively associated with CIMT ( = 0.001). The association remained significant after further adjustment for potential confounders. Strong correlation was found among them as depicted by correlation coefficient (r = 0.779).
Carotid atherosclerosis as measured by IMT is associated with SUA levels in patients with type 2 DM.
本研究旨在探讨2型糖尿病（DM）患者血清尿酸（SUA）水平与颈动脉内膜中层厚度（CIMT）之间的相关性。
本研究是一项于2015年9月至2017年5月对103例糖尿病患者进行的横断面观察性研究。
我们筛选了103例年龄在30 - 65岁之间的2型糖尿病患者，测量其SUA水平和CIMT。根据尿酸水平将患者分为四分位数，对四分位数的CIMT进行比较和分析。
卡方检验、方差分析和Pearson相关性分析。
尿酸水平与CIMT呈正相关（P = 0.001）。在进一步对潜在混杂因素进行调整后，这种关联仍然显著。如相关系数所示（r = 0.779），两者之间存在强相关性。
通过IMT测量的颈动脉粥样硬化与2型糖尿病患者的SUA水平相关。
