• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[氨氯地平/吲达帕胺/培哚普利精氨酸三联固定剂量组合用于动脉高血压的联合治疗:DOKAZATEL'STVO(验证)研究的组织与主要结果]

[Combined Therapy of Arterial Hypertension With Triple Fixed-Dose Combination of Amlodipine/Indapamide/Perindopril Arginine in Real Clinical Practice: the Organization and the Main Results of the DOKAZATEL'STVO (Proof) Study].

作者信息

Kobalava Z D, Troitskaya E A, Tolkacheva V V

机构信息

Federal State Autonomous Educational Institution of Higher Education, "Peoples' Friendship University of Russia".

出版信息

Kardiologiia. 2018 Sep;58(9):21-30.

PMID:30295196
Abstract

AIM

to assess antihypertensive efficacy of the fixed-dose amlodipine/indapamide/perindopril arginine combination in hypertensive patients in real clinical setting.

METHODS

We included in the 3‑month clinical program 1 599 patients with arterial hypertension (AH) (38.8 % men, mean age 61.6±10 years). Primary outcomes were change of office and ambulatory (home blood pressure monitoring) systolic and diastolic blood pressure (SBP and DBP) from baseline to 3 months and rate of achievement of target BP.

摘要

目的

评估氨氯地平/吲达帕胺/培哚普利精氨酸固定剂量复方制剂在实际临床环境中对高血压患者的降压疗效。

方法

我们将1599例动脉高血压(AH)患者纳入为期3个月的临床研究项目(男性占38.8%,平均年龄61.6±10岁)。主要观察指标为从基线到3个月时诊室血压及动态(家庭血压监测)收缩压和舒张压(SBP和DBP)的变化以及血压达标率。

相似文献

1
[Combined Therapy of Arterial Hypertension With Triple Fixed-Dose Combination of Amlodipine/Indapamide/Perindopril Arginine in Real Clinical Practice: the Organization and the Main Results of the DOKAZATEL'STVO (Proof) Study].[氨氯地平/吲达帕胺/培哚普利精氨酸三联固定剂量组合用于动脉高血压的联合治疗:DOKAZATEL'STVO(验证)研究的组织与主要结果]
Kardiologiia. 2018 Sep;58(9):21-30.
2
Fixed-Dose Triple Combination of Antihypertensive Drugs Improves Blood Pressure Control: From Clinical Trials to Clinical Practice.固定剂量三联抗高血压药物组合可改善血压控制:从临床试验到临床实践。
Adv Ther. 2017 Apr;34(4):975-985. doi: 10.1007/s12325-017-0511-1. Epub 2017 Mar 15.
3
The Antihypertensive Efficacy of the Triple Fixed Combination of Perindopril, Indapamide, and Amlodipine: The Results of the PETRA Study.培哚普利、吲达帕胺和氨氯地平三联固定复方的降压疗效:PETRA研究结果
Adv Ther. 2017 Jul;34(7):1753-1763. doi: 10.1007/s12325-017-0572-1. Epub 2017 Jun 23.
4
Triple combination therapy in hypertension: the antihypertensive efficacy of treatment with perindopril, amlodipine, and indapamide SR.高血压的三联组合疗法:培哚普利、氨氯地平和吲达帕胺缓释片联合治疗的降压疗效
Clin Drug Investig. 2014 Oct;34(10):701-8. doi: 10.1007/s40261-014-0223-0.
5
Blood pressure-lowering efficacy and safety of perindopril/indapamide/amlodipine single-pill combination in patients with uncontrolled essential hypertension: a multicenter, randomized, double-blind, controlled trial.培哚普利/吲达帕胺/氨氯地平单片复方制剂治疗血压控制不佳的原发性高血压患者的降压疗效及安全性:一项多中心、随机、双盲、对照试验
J Hypertens. 2017 Jul;35(7):1481-1495. doi: 10.1097/HJH.0000000000001359.
6
Antihypertensive efficacy of triple combination perindopril/indapamide plus amlodipine in high-risk hypertensives: results of the PIANIST study (Perindopril-Indapamide plus AmlodipiNe in high rISk hyperTensive patients).培哚普利/吲达帕胺三联复方加氨氯地平治疗高危高血压患者的降压疗效:PIANIST研究(培哚普利-吲达帕胺加氨氯地平治疗高危高血压患者)结果
Am J Cardiovasc Drugs. 2014 Apr;14(2):137-45. doi: 10.1007/s40256-014-0067-2.
7
[Fixed-Drug Combination Amlodipine, Indapamide and Perindopril: New Horizons of Antihypertensive Therapy].[固定复方氨氯地平、吲达帕胺和培哚普利:抗高血压治疗的新视野]
Kardiologiia. 2017 Apr;57(4):79-88.
8
Effectiveness of Fixed-Dose Perindopril/Amlodipine on Clinic, Ambulatory and Self-Monitored Blood Pressure and Blood Pressure Variability: An Open-Label, Non Comparative Study in the General Practice.固定剂量培哚普利/氨氯地平对诊室、动态及自我监测血压和血压变异性的疗效:一项全科医疗中的开放标签、非对照研究
High Blood Press Cardiovasc Prev. 2015 Dec;22(4):417-25. doi: 10.1007/s40292-015-0117-0. Epub 2015 Sep 9.
9
[Not Available].[无可用内容]。
Kardiologiia. 2018 Nov 24;58(11):63-71. doi: 10.18087/cardio.2018.11.10199.
10
[Therapeutic approaches to the Rational Use of trip-le combination therapy with a fixed combination of amlodipine, indapamide and perindopril arginine (TRIPLE COMBINATION) in patients with hypertension who do not control blood pressure on conventional treatment. (Description and main results of the TRIO program)].[氨氯地平、吲达帕胺和培哚普利精氨酸固定复方三联组合疗法(TRIPLE COMBINATION)在常规治疗血压控制不佳的高血压患者中的合理应用治疗方法。(TRIO项目的描述及主要结果)]
Kardiologiia. 2020 Jun 3;60(5):1149. doi: 10.18087/cardio.2020.5.n1149.

引用本文的文献

1
Perindopril/Indapamide/Amlodipine in Hypertension: A Profile of Its Use.培哚普利/吲达帕胺/氨氯地平治疗高血压:临床应用简介。
Am J Cardiovasc Drugs. 2022 Mar;22(2):219-230. doi: 10.1007/s40256-022-00521-0. Epub 2022 Mar 8.
2
ACEI-induced cough: A review of current evidence and its practical implications for optimal CV risk reduction.血管紧张素转换酶抑制剂(ACEI)所致咳嗽:当前证据的综述及其对最佳心血管风险降低的实际意义。
Indian Heart J. 2020 Sep-Oct;72(5):345-350. doi: 10.1016/j.ihj.2020.08.007. Epub 2020 Aug 10.