Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, 329-0498, Japan.
Nikko Branch, Tochigi Hunter Association, Nikko, Tochigi, 321-2522, Japan.
Virus Res. 2018 Oct 15;258:50-54. doi: 10.1016/j.virusres.2018.10.004. Epub 2018 Oct 5.
The family Circoviridae comprises a large group of small, circular, single-stranded DNA viruses and is classified into two genera: Circovirus and Cyclovirus. They have marked genetic diversity and a broad host range. In this study, three novel circovirus genomes were identified from wild-caught masked palm civets (Paguma larvata) in Japan and classified as a new species within the genus Circovirus based on the demarcation criteria of the International Committee on the Taxonomy of Viruses. Of note, the presence of two predicted introns at the 5'-terminus of the rep gene was suggested in the Paguma larvata circovirus genomes.
Circoviridae 科包含一大组小型、环状、单链 DNA 病毒，分为两个属：Circovirus 和 Cyclovirus。它们具有显著的遗传多样性和广泛的宿主范围。在这项研究中，从日本捕获的野生蒙面棕榈猫（Paguma larvata）中鉴定出三种新型圆环病毒基因组，并根据病毒分类国际委员会的划分标准，将其归类为 Circovirus 属的一个新种。值得注意的是，在 Paguma larvata 圆环病毒基因组的 rep 基因 5'-末端存在两个预测的内含子。
