Service de Gynécologie Endocrinienne et de Médecine de la Reproduction, Hôpital Jeanne de Flandre, CHRU, Lille, France.
Curr Opin Endocrinol Diabetes Obes. 2018 Dec;25(6):377-384. doi: 10.1097/MED.0000000000000445.
Polycystic ovarian syndrome (PCOS) is the most common cause of chronic anovulation and hyperandrogenism in young women and represents a true public health concern and an economic burden.
The pathophysiology of PCOS is still not fully understood, but progresses have been made and the relationships between anti mullerian hormone (AMH), follicle stimulating hormone, luteinizing hormone, E2 and androgens have been explored. The follicle excess plays a central role in the syndrome and AMH is definitively a major component of this phenomena.
The aim of this chapter is to present the recent work studying the role of AMH in the pathophysiology of PCOS and to discuss the improvement that serum AMH assay brings in the diagnosis of PCOS.
多囊卵巢综合征（PCOS）是年轻女性慢性无排卵和高雄激素血症的最常见原因，是真正的公共卫生关注点和经济负担。
PCOS 的病理生理学仍不完全清楚，但已经取得了进展，并且已经探讨了抗苗勒管激素（AMH）、卵泡刺激素、黄体生成素、E2 和雄激素之间的关系。卵泡过多在该综合征中起核心作用，而 AMH 无疑是这一现象的主要组成部分。
本章旨在介绍最近研究 AMH 在 PCOS 病理生理学中的作用的工作，并讨论血清 AMH 检测在 PCOS 诊断中的改进。
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