Formea Christine M, Nicholson Wayne T, Vitek Carolyn Rohrer, Wix Kelly K, McCullough Kristen B, Cunningham Julie L, Zeuli John D, Matey Eric T, Merten Julianna A, Richardson Darcy M, Billings Andrea L, Schramm Garrett E
Department of Pharmacy, Mayo Clinic College of Medicine, Rochester, MN, and Mayo Clinic Hospital-Rochester, Rochester, MN
Department of Anesthesiology, Mayo Clinic Hospital-Rochester, Rochester, MN.
Am J Health Syst Pharm. 2018 Dec 1;75(23):1939-1946. doi: 10.2146/ajhp170771. Epub 2018 Oct 9.
The development, implementation, and evaluation of a pharmacogenomics education program for pharmacists in a large, integrated multicampus health system are described.
Pharmacogenomics has been described as tailoring medications to each patient's unique genetic sequence with the goals of minimizing harmful effects and optimizing therapeutic effects. Pharmacists are uniquely trained to lead the implementation of pharmacogenomics in clinical care. After assessment of pharmacists' comfort with pharmacogenomics, different approaches were explored to develop, pilot test, and disseminate pharmacogenomics education across a multicampus academic medical center. Limited success with large-audience, single-lecture didactic education led to development and delivery of targeted, competency-based online modules using the institution's academic virtual learning environment and course management system. Implementation steps included (1) collaboration with the Mayo Clinic Center for Individualized Medicine to create an interprofessional development team and project charter, (2) galvanizing pharmacy leadership support across multiple campuses, (3) development of competency-based interactive modules, and (4) assessment of the quality of and learner satisfaction with the modules. Significant improvements in competency scores were observed with each module and across the multiple campuses. Satisfaction with the education program was assessed at the end of a 4-module series.
A pharmacogenomics educational program targeting pharmacists was developed through interprofessional collaboration and provided a novel opportunity to construct an educational infrastructure to support enterprise health-system campuses with limited educational resources.
描述了在一个大型综合多校区卫生系统中为药剂师开展的药物基因组学教育项目的开发、实施和评估情况。
药物基因组学被描述为根据每个患者独特的基因序列来定制药物，以达到将有害影响降至最低并优化治疗效果的目的。药剂师经过专门培训，能够在临床护理中引领药物基因组学的实施。在评估了药剂师对药物基因组学的熟悉程度后，探索了不同方法，以在一个多校区学术医疗中心开展、试点测试并推广药物基因组学教育。面向大众的单一讲座式理论教育取得的成功有限，这促使我们利用该机构的学术虚拟学习环境和课程管理系统，开发并提供有针对性的、基于能力的在线模块。实施步骤包括：（1）与梅奥诊所个性化医疗中心合作，组建一个跨专业的开发团队并制定项目章程；（2）在多个校区争取药房领导层的支持；（3）开发基于能力的互动模块；（4）评估这些模块的质量和学习者满意度。每个模块以及在多个校区，能力得分都有显著提高。在一个由四个模块组成的系列课程结束时，对该教育项目的满意度进行了评估。
通过跨专业合作，开发了一个针对药剂师的药物基因组学教育项目，为利用有限的教育资源构建支持企业卫生系统各校区的教育基础设施提供了一个新机会。
