• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Implementing Pharmacogenomics Clinical Decision Support: A Comprehensive Tutorial on how to Integrate the Epic Genomics Module.实施药物基因组学临床决策支持:关于如何整合Epic基因组学模块的全面教程。
Clin Pharmacol Ther. 2025 Jun;117(6):1670-1681. doi: 10.1002/cpt.3599. Epub 2025 Feb 17.
2
How to Implement Digital Clinical Consultations in UK Maternity Care: the ARM@DA Realist Review.如何在英国产科护理中实施数字临床会诊:ARM@DA实证主义综述
Health Soc Care Deliv Res. 2025 May 21:1-77. doi: 10.3310/WQFV7425.
3
Implementation of a Quality Improvement and Clinical Decision Support Tool for Cancer Diagnosis in Primary Care: Process Evaluation.基层医疗中癌症诊断质量改进与临床决策支持工具的实施:过程评估
JMIR Cancer. 2025 Jun 12;11:e65461. doi: 10.2196/65461.
4
Does Pharmacogenomic Testing Improve Clinical Outcomes for Major Depressive Disorder? A Systematic Review of Clinical Trials and Cost-Effectiveness Studies.药物基因组学检测能否改善重度抑郁症的临床结局?一项关于临床试验和成本效益研究的系统评价。
J Clin Psychiatry. 2017 Jun;78(6):720-729. doi: 10.4088/JCP.15r10583.
5
The use of Open Dialogue in Trauma Informed Care services for mental health consumers and their family networks: A scoping review.创伤知情护理服务中使用开放对话模式为心理健康消费者及其家庭网络提供服务:范围综述。
J Psychiatr Ment Health Nurs. 2024 Aug;31(4):681-698. doi: 10.1111/jpm.13023. Epub 2024 Jan 17.
6
Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts.将药物遗传学数据整合到Epic基因组模块中可驱动临床决策支持警报。
Front Pharmacol. 2024 Dec 20;15:1458095. doi: 10.3389/fphar.2024.1458095. eCollection 2024.
7
Designing Clinical Decision Support Systems (CDSS)-A User-Centered Lens of the Design Characteristics, Challenges, and Implications: Systematic Review.设计临床决策支持系统(CDSS)——基于用户中心视角的设计特征、挑战及影响:系统评价
J Med Internet Res. 2025 Jun 20;27:e63733. doi: 10.2196/63733.
8
Pharmacogenomics and risk stratification in cardiovascular care: Insights from randomized controlled trials.心血管护理中的药物基因组学与风险分层:来自随机对照试验的见解
Medicine (Baltimore). 2025 Jun 13;104(24):e42868. doi: 10.1097/MD.0000000000042868.
9
Assessing the comparative effects of interventions in COPD: a tutorial on network meta-analysis for clinicians.评估慢性阻塞性肺疾病干预措施的比较效果:面向临床医生的网状Meta分析教程
Respir Res. 2024 Dec 21;25(1):438. doi: 10.1186/s12931-024-03056-x.
10
Nano-enabled pharmacogenomics: revolutionizing personalized drug therapy.纳米技术支持的药物基因组学:变革个性化药物治疗
J Biomater Sci Polym Ed. 2025 May;36(7):913-938. doi: 10.1080/09205063.2024.2431426. Epub 2024 Nov 26.

引用本文的文献

1
Drug-Gene Interactions and Clinical Outcomes After Vascular Surgery in the Million Veteran Program.百万退伍军人计划中血管手术后的药物-基因相互作用及临床结局
JAMA Surg. 2025 Jun 4. doi: 10.1001/jamasurg.2025.1503.

本文引用的文献

1
Clinical decision making: validation of the nursing anxiety and self-confidence with clinical decision making scale (NASC-CDM ©) into Spanish and comparative cross-sectional study in nursing students.临床决策:将护理焦虑与临床决策自信量表(NASC-CDM ©)翻译成西班牙语并在护理专业学生中进行比较横断面研究以验证该量表
BMC Nurs. 2024 Apr 24;23(1):265. doi: 10.1186/s12912-024-01917-w.
2
Clinician Response to Pharmacogenetic Clinical Decision Support Alerts.临床医生对药物基因组学临床决策支持警报的反应。
Clin Pharmacol Ther. 2023 Dec;114(6):1350-1357. doi: 10.1002/cpt.3051. Epub 2023 Nov 2.
3
The effectiveness of a health education intervention to reduce anxiety in quarantined COVID-19 patients: a randomized controlled trial.健康教育干预对减轻 COVID-19 隔离患者焦虑的有效性:一项随机对照试验。
BMC Public Health. 2023 Jun 20;23(1):1188. doi: 10.1186/s12889-023-16104-w.
4
Pharmacogenomics in practice: a review and implementation guide.实践中的药物基因组学:综述与实施指南。
Front Pharmacol. 2023 May 18;14:1189976. doi: 10.3389/fphar.2023.1189976. eCollection 2023.
5
Implementation of CYP2C19 genotyping to guide proton pump inhibitor use at an academic health center.在学术医疗中心实施 CYP2C19 基因分型以指导质子泵抑制剂的使用。
Am J Health Syst Pharm. 2023 Jul 21;80(15):994-1003. doi: 10.1093/ajhp/zxad099.
6
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin Reuptake Inhibitor Antidepressants.临床药物遗传学实施联盟(CPIC)CYP2D6、CYP2C19、CYP2B6、SLC6A4 和 HTR2A 基因型及 5-羟色胺再摄取抑制剂类抗抑郁药指南
Clin Pharmacol Ther. 2023 Jul;114(1):51-68. doi: 10.1002/cpt.2903. Epub 2023 May 30.
7
A retrospective study of differences in patients' anxiety and satisfaction between paper-based and computer-based tools for "Shared Decision-Making".一项回顾性研究比较了“共同决策”中纸质工具和计算机工具在患者焦虑和满意度方面的差异。
Sci Rep. 2023 Mar 30;13(1):5187. doi: 10.1038/s41598-023-32448-0.
8
How to Implement a Pharmacogenetics Service at your Institution.如何在您的机构开展药物遗传学服务。
J Am Coll Clin Pharm. 2022 Nov;5(11):1161-1175. doi: 10.1002/jac5.1699. Epub 2022 Aug 27.
9
Clinical pharmacogenomic testing and reporting: A technical standard of the American College of Medical Genetics and Genomics (ACMG).临床药物基因组学检测与报告:美国医学遗传学与基因组学学会(ACMG)技术标准。
Genet Med. 2022 Apr;24(4):759-768. doi: 10.1016/j.gim.2021.12.009. Epub 2022 Feb 10.
10
A Novel Approach to Improve Accuracy of CYP2D6 Enzyme Activity and Drug Response Predictions.一种提高CYP2D6酶活性和药物反应预测准确性的新方法。
Clin Chem. 2022 May 18;68(5):616-618. doi: 10.1093/clinchem/hvab269.

实施药物基因组学临床决策支持:关于如何整合Epic基因组学模块的全面教程。

Implementing Pharmacogenomics Clinical Decision Support: A Comprehensive Tutorial on how to Integrate the Epic Genomics Module.

作者信息

Hall Bradley T, Eken Eda, Cavallari Larisa H, Duarte Julio D, Wiisanen Kristin W, Cicali Emily J, Nguyen Khoa A

机构信息

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville, FL, USA.

Center for Pharmacogenomics and Precision Medicine, University of Florida, Gainesville, FL, USA.

出版信息

Clin Pharmacol Ther. 2025 Jun;117(6):1670-1681. doi: 10.1002/cpt.3599. Epub 2025 Feb 17.

DOI:10.1002/cpt.3599
PMID:39960348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12183801/
Abstract

In the past decade, pharmacogenomic (PGx) testing to predict drug response have emerged into clinical care. Clinical decision support (CDS) has and continues to play a key role in educating prescribers and facilitating the integration of pharmacogenomic results into routine clinical practice. The Epic Genomics module, an add-on to Epic's base clinical software, allows for storage of structured genomic data and provides electronic heath record tools designed with PGx CDS implementation in mind. In early 2022, the University of Florida Health deployed the Genomics module. This tutorial outlines the steps taken by the University of Florida Health Precision Medicine Program to implement Epic's Genomic Module at University of Florida Health and identifies key factors for a successful implementation.

摘要

在过去十年中,用于预测药物反应的药物基因组学(PGx)检测已进入临床护理领域。临床决策支持(CDS)过去一直并将继续在培训开处方者以及促进将药物基因组学结果整合到常规临床实践中发挥关键作用。Epic基因组学模块是Epic基础临床软件的一个附加组件,可存储结构化基因组数据,并提供在设计时考虑到PGx CDS实施的电子健康记录工具。2022年初,佛罗里达大学健康中心部署了基因组学模块。本教程概述了佛罗里达大学健康精准医学项目在佛罗里达大学健康中心实施Epic基因组学模块所采取的步骤,并确定了成功实施的关键因素。