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咀嚼作为预防认知功能障碍的一种手段。

Mastication as a tool to prevent cognitive dysfunctions.

作者信息

Krishnamoorthy Gayathri, Narayana Aparna I, Balkrishanan Dhanasekar

机构信息

Department of Prosthodontics and Crown & Bridge, Manipal College of Dental Sciences, Manipal University, Manipal, 576104 India.

出版信息

Jpn Dent Sci Rev. 2018 Nov;54(4):169-173. doi: 10.1016/j.jdsr.2018.06.001. Epub 2018 Aug 31.

Abstract

Mastication as we all know has always been related to its primary function of digestion, but little do we know that it produces an enhancing effect on general health, especially the cognitive performance related aspects of memory. Recent studies have shown its association with activation of various brain regions, however little is known about its effects on neuronal activity in these specified regions. According to the enormous evidences collected so far, mastication has proved to be effective in conducting huge amount of sensory information to the brain, and maintaining learning and memory functions of hippocampus. Therefore it is essential that we maintain normal occlusion and preserve the masticatory function as long as possible to prevent the attenuation of hippocampus, caused by occlusal disharmony and reduced mastication. We provide an overview on how mastication activates various cortical areas of the brain and how an increase in the cerebral blood oxygen level of hippocampus and prefrontal cortex (PFC) accentuates the learning and memory process. We also justify why maintaining and establishing a normal occlusion is important from neurological point of view.

摘要

众所周知,咀嚼一直与其消化的主要功能相关,但我们鲜少知道它对整体健康有增强作用,尤其是对与记忆相关的认知表现方面。最近的研究表明它与大脑各区域的激活有关,然而对于它在这些特定区域对神经元活动的影响却知之甚少。根据目前收集到的大量证据,咀嚼已被证明能有效地将大量感官信息传导至大脑,并维持海马体的学习和记忆功能。因此,至关重要的是,我们要尽可能保持正常咬合并保留咀嚼功能,以防止因咬合不协调和咀嚼减少导致的海马体衰退。我们概述了咀嚼如何激活大脑的各个皮质区域,以及海马体和前额叶皮质(PFC)脑血氧水平的增加如何强化学习和记忆过程。我们还阐述了从神经学角度来看,维持和建立正常咬合为何重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4758/6175965/87af51522b31/gr1.jpg

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