θ 相协调的记忆再激活在 NREM 睡眠期间的慢振荡节律中再次出现。
Theta Phase-Coordinated Memory Reactivation Reoccurs in a Slow-Oscillatory Rhythm during NREM Sleep.
机构信息
Centre for Human Brain Health, School of Psychology, University of Birmingham, Birmingham, UK; Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands.
Kavli Institute for Systems Neuroscience, Centre for Neural Computation, The Egil and Pauline Braathen and Fred Kavli Centre for Cortical Microcircuits, Norwegian University of Science and Technology, NTNU, Trondheim, Norway; Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
出版信息
Cell Rep. 2018 Oct 9;25(2):296-301. doi: 10.1016/j.celrep.2018.09.037.
Abstract
It has been proposed that sleep's contribution to memory consolidation is to reactivate prior encoded information. To elucidate the neural mechanisms carrying reactivation-related mnemonic information, we investigated whether content-specific memory signatures associated with memory reactivation during wakefulness reoccur during subsequent sleep. We show that theta oscillations orchestrate the reactivation of memories during both wakefulness and sleep. Reactivation patterns during sleep autonomously re-emerged at a rate of ∼1 Hz, indicating a coordination by slow oscillatory activity.
摘要
有人提出，睡眠对记忆巩固的贡献是重新激活先前编码的信息。为了阐明与清醒时记忆再激活相关的记忆信息的神经机制，我们研究了与清醒时记忆再激活相关的特定内容的记忆特征是否会在随后的睡眠中再次出现。我们发现，θ 振荡协调了清醒和睡眠期间记忆的再激活。睡眠期间的再激活模式以约 1 Hz 的速率自主重新出现，表明由慢振荡活动进行协调。
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