再生医学：驯服嵌合体。

Regenerative Medicine: Taming the Chimaera.

机构信息

Department of Farm Animal Health, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 104, 3584CM Utrecht, the Netherlands.

出版信息

Stem Cell Reports. 2018 Oct 9;11(4):849-851. doi: 10.1016/j.stemcr.2018.09.003.

DOI:10.1016/j.stemcr.2018.09.003

PMID:30304697

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6178845/

Abstract

In this issue of Stem Cell Reports, Hamanaka et al. (2018) describe the generation of chimeric mice with all vascular endothelial cells derived from pluripotent stem cells. This approach is desirable to prevent immune rejection when human stem cells are combined with animal embryos to grow human organs in animals.

摘要

在本期的《Stem Cell Reports》中，Hamanaka 等人（2018）描述了生成所有血管内皮细胞均源自多能干细胞的嵌合小鼠的方法。当将人类干细胞与动物胚胎结合以在动物体内生长人类器官时，这种方法有利于防止免疫排斥。