糖尿病足溃疡评估与管理的当前概念
Current concepts for the evaluation and management of diabetic foot ulcers.
作者信息
Mavrogenis Andreas F, Megaloikonomos Panayiotis D, Antoniadou Thekla, Igoumenou Vasilios G, Panagopoulos Georgios N, Dimopoulos Leonidas, Moulakakis Konstantinos G, Sfyroeras George S, Lazaris Andreas
机构信息
First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece.
Department of Vascular Surgery, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece.
出版信息
EFORT Open Rev. 2018 Sep 27;3(9):513-525. doi: 10.1302/2058-5241.3.180010. eCollection 2018 Sep.
The lifetime risk for diabetic patients to develop a diabetic foot ulcer (DFU) is 25%. In these patients, the risk of amputation is increased and the outcome deteriorates.More than 50% of non-traumatic lower-extremity amputations are related to DFU infections and 85% of all lower-extremity amputations in patients with diabetes are preceded by an ulcer; up to 70% of diabetic patients with a DFU-related amputation die within five years of their amputation.Optimal management of patients with DFUs must include clinical awareness, adequate blood glucose control, periodic foot inspection, custom therapeutic footwear, off-loading in high-risk patients, local wound care, diagnosis and control of osteomyelitis and ischaemia. Cite this article: 2018;3:513-525. DOI: 10.1302/2058-5241.3.180010.
糖尿病患者发生糖尿病足溃疡（DFU）的终生风险为25%。在这些患者中，截肢风险增加，病情恶化。超过50%的非创伤性下肢截肢与DFU感染有关，糖尿病患者所有下肢截肢中有85%在截肢前有溃疡；高达70%因DFU相关截肢的糖尿病患者在截肢后五年内死亡。DFU患者的最佳管理必须包括临床意识、充分的血糖控制、定期足部检查、定制治疗性鞋具、高危患者减负、局部伤口护理、骨髓炎和缺血的诊断与控制。引用本文：2018；3：513 - 525。DOI：10.1302/2058 - 5241.3.180010。
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