从启动的祖细胞在小鼠中生成功能性人类脂肪组织。
Generation of Functional Human Adipose Tissue in Mice from Primed Progenitor Cells.
机构信息
1 Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.
2 Department of Surgery, University of Massachusetts Medical School and UMASS Memorial Medical Center, Worcester, Massachusetts.
出版信息
Tissue Eng Part A. 2019 Jun;25(11-12):842-854. doi: 10.1089/ten.TEA.2018.0067. Epub 2019 Jan 4.
Abstract
This research describes the use of human mesenchymal progenitor cells for generating functional adipose tissue in a nude mouse model. Further preclinical development of the methods and insights described in this article can lead to therapeutic use of these cells in regenerative and reconstructive medicine.
摘要
本研究描述了利用人骨髓间充质祖细胞在裸鼠模型中生成功能性脂肪组织的方法。本文所描述的方法和研究结果的进一步临床前开发，可以推动这些细胞在再生和重建医学中的治疗应用。
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