Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO.
Department of Medicine, Division of Oncology, Washington University School of Medicine, St Louis, MO.
Am J Clin Pathol. 2019 Jan 7;151(2):185-193. doi: 10.1093/ajcp/aqy126.
Bone marrow biopsies are essential for evaluating patients with suspected or confirmed hematopoietic disorders or malignancies, but little is known about how biopsy needle type affects biopsy length and/or quality. We sought to compare bone marrow biopsy quality in specimens obtained with two different needles.
A retrospective analysis was performed on bone marrow specimens obtained with manual single-bevel (n = 114) or triple-bevel (n = 166) needles. The lengths of evaluable marrow, core quality, and aspirate quality were assessed by blinded hematopathologists.
The triple-bevel needle produced 1.33-mm shorter lengths of evaluable marrow than the single-bevel needle and was five times less likely to produce a specimen rated as "adequate" and 4.2 times more likely to produce crush artifact. The triple-bevel needle was also 2.4 times more likely to produce hemodilute aspirates.
Bone marrow biopsy needle type affects the length of evaluable marrow and quality of core and aspirate specimens.
骨髓活检对于评估疑似或确诊的造血系统疾病或恶性肿瘤患者至关重要，但对于活检针类型如何影响活检长度和/或质量知之甚少。我们旨在比较两种不同类型的活检针获得的骨髓活检标本的质量。
对使用手动单斜面（n=114）或三斜面（n=166）活检针获得的骨髓标本进行回顾性分析。由盲法血液病理学家评估可评估骨髓的长度、芯质量和抽吸物质量。
与单斜面针相比，三斜面针产生的可评估骨髓长度短 1.33mm，产生“足够”评分标本的可能性低 5 倍，产生压碎伪影的可能性高 4.2 倍。三斜面针也更有可能产生血液稀释的抽吸物。
骨髓活检针类型会影响可评估骨髓的长度以及芯和抽吸物标本的质量。
