van Dongen J A, Bartelink H, Fentiman I S, Peterse J L
Eur J Surg Oncol. 1987 Apr;13(2):123-5.
The incidence of ductal carcinoma in situ of the breast (DCIS) is low. Multifocality and difficulties in defining the extent of the disease are the main problems in relation to the therapy. Biologic characterization still is incomplete. Ablative treatment gives a 100% cure. Prospective trials are needed to evaluate breast conserving therapy.
乳腺导管原位癌（DCIS）的发病率较低。多灶性以及界定疾病范围的困难是与治疗相关的主要问题。生物学特征仍不完整。消融治疗可实现100%治愈。需要进行前瞻性试验来评估保乳治疗。
