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Targeted next generation sequencing reveals high mutation frequency of and in high-grade B-cell lymphoma with and and/or rearrangements.

作者信息

Evrard Solène M, Péricart Sarah, Grand David, Amara Nadia, Escudié Frédéric, Gilhodes Julia, Bories Pierre, Traverse-Glehen Alexandra, Dubois Romain, Brousset Pierre, Parrens Marie, Laurent Camille

机构信息

Pathology and Cytology Department, CHU Toulouse, IUCT Oncopole

Toulouse III Paul Sabatier University.

出版信息

Haematologica. 2019 Apr;104(4):e154-e157. doi: 10.3324/haematol.2018.198572. Epub 2018 Oct 11.

DOI:10.3324/haematol.2018.198572
PMID:30309852
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6442958/
Abstract
摘要

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本文引用的文献

1
Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.弥漫性大 B 细胞淋巴瘤的分子亚型与不同的发病机制和预后相关。
Nat Med. 2018 May;24(5):679-690. doi: 10.1038/s41591-018-0016-8. Epub 2018 Apr 30.
2
Genetics and Pathogenesis of Diffuse Large B-Cell Lymphoma.弥漫性大B细胞淋巴瘤的遗传学与发病机制
N Engl J Med. 2018 Apr 12;378(15):1396-1407. doi: 10.1056/NEJMoa1801445.
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Assessment of Capture and Amplicon-Based Approaches for the Development of a Targeted Next-Generation Sequencing Pipeline to Personalize Lymphoma Management.评估基于捕获和扩增子的方法，以开发针对淋巴瘤管理的个体化靶向下一代测序管道。
J Mol Diagn. 2018 Mar;20(2):203-214. doi: 10.1016/j.jmoldx.2017.11.010. Epub 2018 Feb 8.
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Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma.弥漫性大B细胞淋巴瘤的遗传和功能驱动因素
Cell. 2017 Oct 5;171(2):481-494.e15. doi: 10.1016/j.cell.2017.09.027.
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Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets.将弥漫性大 B 细胞淋巴瘤中的基因组改变进行整合，可鉴定出新的相关途径和潜在的治疗靶点。
Leukemia. 2018 Mar;32(3):675-684. doi: 10.1038/leu.2017.251. Epub 2017 Aug 14.
6
Genetic profiling of and in diffuse large B-cell lymphoma determines cell-of-origin-specific clinical impact.弥漫性大 B 细胞淋巴瘤中 和 的基因谱分析决定了细胞起源特异性的临床影响。
Blood. 2017 May 18;129(20):2760-2770. doi: 10.1182/blood-2016-11-747022. Epub 2017 Mar 28.
7
Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B cell lymphoma: mutational analysis of the SAKK 38/07 prospective clinical trial cohort.CREBBP和SOCS1突变是弥漫性大B细胞淋巴瘤的独立预后因素：SAKK 38/07前瞻性临床试验队列的突变分析
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Clin Cancer Res. 2016 Jun 15;22(12):2919-28. doi: 10.1158/1078-0432.CCR-15-2305. Epub 2016 Jan 27.
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Impact of oncogene rearrangement patterns on outcomes in patients with double-hit non-Hodgkin lymphoma.致癌基因重排模式对双打击非霍奇金淋巴瘤患者预后的影响。
Cancer. 2016 Feb 15;122(4):559-64. doi: 10.1002/cncr.29781. Epub 2015 Nov 13.
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MYC/BCL6 double-hit lymphoma (DHL): a tumour associated with an aggressive clinical course and poor prognosis.MYC/BCL6 双打击淋巴瘤（DHL）：一种与侵袭性临床病程和不良预后相关的肿瘤。
Histopathology. 2016 Jun;68(7):1090-8. doi: 10.1111/his.12884. Epub 2015 Dec 8.