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一项关于急性细菌性皮肤和皮肤结构感染的调查研究中,急诊医学提供者在医院收治和抗生素治疗决策上的差异:抗菌药物管理教育的机会

Variability in Emergency Medicine Provider Decisions on Hospital Admission and Antibiotic Treatment in a Survey Study for Acute Bacterial Skin and Skin Structure Infections: Opportunities for Antimicrobial Stewardship Education.

作者信息

Almarzoky Abuhussain Safa S, Burak Michelle A, Adams Danyel K, Kohman Kelsey N, Tart Serina B, Hobbs Athena L V, Jacknin Gabrielle, Nailor Michael D, Keyloun Katelyn R, Nicolau David P, Kuti Joseph L

机构信息

Center for Anti-Infective Research and Development, Hartford Hospital, Hartford, Connecticut.

Umm Al-Qura University, Makkah, Saudi Arabia.

出版信息

Open Forum Infect Dis. 2018 Oct 8;5(10):ofy206. doi: 10.1093/ofid/ofy206. eCollection 2018 Oct.

Abstract

BACKGROUND

Acute bacterial skin and skin structure infections (ABSSSIs) are a frequent cause of emergency department (ED) visits. Providers in the ED have many decisions to make during the initial treatment of ABSSSI. There are limited data on the patient factors that influence these provider decisions.

METHODS

An anonymous survey was administered to providers at 6 EDs across the United States. The survey presented patient cases with ABSSSIs ≥75 cm and escalating clinical scenarios including relapse, controlled diabetes, and sepsis. For each case, participants were queried on their decision for admission vs discharge and antibiotic therapy (intravenous, oral, or both) and to rank the factors that influenced their antibiotic decision.

RESULTS

The survey was completed by 130 providers. For simple ABSSSI, the majority of providers chose an oral antibiotic and discharged patients home. The presence of recurrence or controlled diabetes resulted in more variation in responses. Thirty-four (40%) and 51 (60%) providers chose intravenous followed by oral antibiotics and discharged the recurrence and diabetes cases, respectively. Presentation with sepsis resulted in initiation with intravenous antibiotics (122, 95.3%) and admission (125, 96.1%) in most responses.

CONCLUSIONS

Variability in responses to certain patient scenarios suggests opportunities for education of providers in the ED and the development of an ABSSSI clinical pathway to help guide treatment.

摘要

背景

急性细菌性皮肤和皮肤结构感染(ABSSSI)是急诊科就诊的常见原因。急诊科的医护人员在ABSSSI的初始治疗过程中需要做出许多决策。关于影响这些医护人员决策的患者因素的数据有限。

方法

对美国6家急诊科的医护人员进行了一项匿名调查。该调查展示了ABSSSI面积≥75平方厘米的患者病例以及不断升级的临床情况,包括复发、控制不佳的糖尿病和脓毒症。对于每个病例,询问参与者关于收治与出院的决定以及抗生素治疗(静脉注射、口服或两者皆用),并对影响其抗生素决策的因素进行排序。

结果

130名医护人员完成了调查。对于单纯性ABSSSI,大多数医护人员选择口服抗生素并让患者出院。复发或控制不佳的糖尿病情况导致回答的差异更大。34名(40%)和51名(60%)医护人员分别选择先静脉注射后口服抗生素,并让复发和糖尿病病例出院。出现脓毒症时,大多数回答是开始使用静脉注射抗生素(122例,95.3%)并收治入院(125例,96.1%)。

结论

对某些患者情况的回答存在差异,这表明有机会对急诊科的医护人员进行教育,并制定ABSSSI临床路径以帮助指导治疗。

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