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急诊科皮肤及软组织感染的指南与实际管理

Guidelines vs Actual Management of Skin and Soft Tissue Infections in the Emergency Department.

作者信息

Kamath Rahul S, Sudhakar Deepthi, Gardner Julianna G, Hemmige Vagish, Safar Hossam, Musher Daniel M

机构信息

Department of Medicine, Baylor College of Medicine, Houston, Texas.

Emergency Medicine Service Line, Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas.

出版信息

Open Forum Infect Dis. 2018 Jan 12;5(1):ofx188. doi: 10.1093/ofid/ofx188. eCollection 2018 Jan.

Abstract

BACKGROUND

Infections of skin and soft tissue (SSTI) commonly cause visits to hospital emergency departments (EDs). The Infectious Diseases Society of America (IDSA) has published guidelines for the management of SSTI, but it is unclear how closely these guidelines are followed in practice.

METHODS

We reviewed records of patients seen in the ED at a large tertiary care hospital to determine guidelines adherence in 4 important areas: the decision to hospitalize, choice of antibiotics, incision and drainage (I&D) of abscesses, and submission of specimens for culture.

RESULTS

The decision to hospitalize did not comply with guidelines in 19.6% of cases. Nonrecommended antibiotics were begun in the ED in 71% of patients with nonpurulent infections and 68.4% of patients with purulent infections. Abscesses of mild severity were almost always treated with antibiotics, and I&D was often not done (both against recommendations). Blood cultures were done (against recommendations) in 29% of patients with mild-severity cellulitis. Abscess drainage was almost always sent for culture (recommendations neither favor nor oppose). Overall, treatment fully complied with guidelines in 20.1% of cases.

CONCLUSIONS

Our results show a striking lack of concordance with IDSA guidelines in the ED management of SSTI. Social factors may account for discordant decisions regarding site of care. Use of trimethoprim/sulfamethoxazole (TMP/SMX) in cellulitis was the most common source of discordance; this practice is supported by some medical literature. Excess antibiotics were often used in cellulitis and after I&D of simple abscesses, opposing antibiotic stewardship. Ongoing education of ED doctors and continued review of published guidelines are needed.

摘要

背景

皮肤和软组织感染(SSTI)常导致患者前往医院急诊科就诊。美国传染病学会(IDSA)已发布SSTI管理指南,但尚不清楚这些指南在实际应用中的遵循程度。

方法

我们回顾了一家大型三级医疗中心急诊科患者的记录,以确定在四个重要方面对指南的遵循情况:住院决策、抗生素选择、脓肿切开引流(I&D)以及送检培养标本。

结果

19.6%的病例住院决策不符合指南。71%的非化脓性感染患者和68.4%的化脓性感染患者在急诊科开始使用了不推荐的抗生素。轻度脓肿几乎总是使用抗生素治疗,且常常未进行切开引流(均与推荐意见相悖)。29%的轻度蜂窝织炎患者进行了血培养(与推荐意见相悖)。脓肿引流几乎总是送检培养(推荐意见未支持也未反对)。总体而言,20.1%的病例治疗完全符合指南。

结论

我们的结果表明,在急诊科对SSTI的管理中,与IDSA指南存在显著差异。社会因素可能导致护理地点决策不一致。在蜂窝织炎中使用甲氧苄啶/磺胺甲恶唑(TMP/SMX)是最常见的不一致来源;这种做法得到了一些医学文献的支持。蜂窝织炎和单纯脓肿切开引流后常过度使用抗生素,这与抗生素管理相悖。需要对急诊科医生持续开展教育并持续审查已发布的指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ab1/5767964/e492861c6b7a/ofx18801.jpg

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