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儿童麻疹的临床特征,特别提及婴儿

Clinical profile of measles in children with special reference to infants.

作者信息

Sindhu T G, Geeta M G, Krishnakumar P, Sabitha S, Ajina K K

机构信息

1 Associate Professor, Department of Paediatrics, Government Medical College, Kozhikode, Kerala, India.

2 Additional Professor, Department of Paediatrics, Government Medical College, Kozhikode, Kerala, India.

出版信息

Trop Doct. 2019 Jan;49(1):20-23. doi: 10.1177/0049475518804695. Epub 2018 Oct 14.

Abstract

This study was conducted to analyse the clinical characteristics of measles in infants and to compare them with those in older children. Clinical and sociodemographic details of all hospitalised children with suspected measles were recorded and confirmed cases were analysed further. Twenty-four infants and 34 children aged >1 year were included. Most infants were boys and 15 (62.5%) of them were aged <9 months. Early onset of rash (within three days of fever in 62.5% of cases) occurred in infants. The complications of measles in infants included bronchopneumonia (n = 17, 71%), acute diarrhoea (n = 8, 33%), meningitis (n = 1, 4%) and staphylococcal sepsis (n = 2, 8%). The number of infants with complications was significantly high (88% and 65%; P = 0.05). Measles in infants can have atypical presentations, a greater risk for complications and may occur before they are due to receive the conventional first dose of measles vaccine.

摘要

本研究旨在分析婴儿麻疹的临床特征,并与大龄儿童的麻疹临床特征进行比较。记录了所有疑似麻疹住院儿童的临床和社会人口学详细信息,并对确诊病例进行了进一步分析。纳入了24名婴儿和34名年龄大于1岁的儿童。大多数婴儿为男孩,其中15名(62.5%)年龄小于9个月。婴儿出现皮疹较早(62.5%的病例在发热三天内出现皮疹)。婴儿麻疹的并发症包括支气管肺炎(n = 17,71%)、急性腹泻(n = 8,33%)、脑膜炎(n = 1,4%)和葡萄球菌败血症(n = 2,8%)。有并发症的婴儿数量显著较高(88%和65%;P = 0.05)。婴儿麻疹可能有非典型表现,并发症风险更高,且可能在应接种常规第一剂麻疹疫苗之前就已发生。

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