Katims J J, Naviasky E H, Rendell M S, Ng L K, Bleecker M L
Arch Phys Med Rehabil. 1987 Apr;68(4):210-3.
We have evaluated various forms of peripheral neuropathy with a new device which emits a constant sinusoid stimulus at varying frequencies to quantitate current perception thresholds (CPTs). In normal individuals, CPT measures increase with increasing stimulation frequency, are highest on the toe and lowest on the face. There is a significant effect of age and sex on threshold perception. In patients with neuropathy, there is a marked increase in thresholds on hands and feet, as well as a lesser but still significant increase of facial CPTs. Thresholds furthermore correlated with clinical severity in a group of patients with diabetic neuropathy. Facial thresholds were markedly elevated in the patients with moderate to severe neuropathy, suggesting that the device is sensitive to the systemic nature of peripheral neuropathy. The authors believe the device will be a useful tool in screening for sensory neurologic abnormalities.
我们使用一种新设备评估了各种形式的周围神经病变，该设备以不同频率发出恒定的正弦刺激，以定量电流感觉阈值（CPT）。在正常个体中，CPT测量值随刺激频率增加而升高，在脚趾处最高，在面部最低。年龄和性别对阈值感知有显著影响。在神经病变患者中，手和脚的阈值显著升高，面部CPT也有较小但仍显著的升高。此外，在一组糖尿病神经病变患者中，阈值与临床严重程度相关。中度至重度神经病变患者的面部阈值明显升高，表明该设备对周围神经病变的全身性敏感。作者认为该设备将成为筛查感觉神经异常的有用工具。
