Vizi E S, Ronai A, Bernath S
Biochem Pharmacol. 1987 Mar 15;36(6):803-7. doi: 10.1016/0006-2952(87)90167-5.
The effect of p-nitrophenylphosphate (p-NPP) on the release of acetylcholine evoked by drugs and ionic environments known to inhibit Na+, K+-ATPase was studied in isolated cortical slices of rat brain and longitudinal muscle strip of guinea-pig ileum. p-NPP inhibited the release of acetylcholine induced by sodium deprivation provided that the circumstances were in favour of the function of the K+-activated part of ATPase. However, it failed to antagonize the increase in the acetylcholine release elicited by omission of K+ or by administration of ouabain. Therefore it is concluded that the K+-stimulated phosphatase moiety of the Na+, K+-ATPase might be involved in the release of acetylcholine.
在大鼠脑分离皮质切片和豚鼠回肠纵肌条中，研究了对硝基苯磷酸酯（p-NPP）对已知抑制Na⁺、K⁺-ATP酶的药物和离子环境所诱发的乙酰胆碱释放的影响。如果条件有利于ATP酶的钾激活部分的功能，p-NPP可抑制钠缺乏诱导的乙酰胆碱释放。然而，它不能拮抗因缺钾或给予哇巴因引起的乙酰胆碱释放增加。因此得出结论，Na⁺、K⁺-ATP酶的钾刺激磷酸酶部分可能参与乙酰胆碱的释放。
