Ignatov Iu D, Zaĭtsev A A
Biull Eksp Biol Med. 1987 Apr;103(4):420-2.
The experiments on alert rats have shown that dissociation in opioid regulation of behavioural and hemodynamic pain manifestations is determined at a spinal opiate receptor level. Opiates and opioids suppress blood pressure nociceptive reactions to mu-opiate receptors, while sigma-opiate receptors are involved into the generation of autonomic activating effect in opiate analgesia.
对警觉大鼠的实验表明,阿片类物质对行为性和血流动力学疼痛表现的调节解离是在脊髓阿片受体水平上确定的。阿片类药物和阿片肽抑制对μ阿片受体的血压伤害性反应,而σ阿片受体参与阿片类镇痛中自主激活效应的产生。