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绿色激光治疗——阈下绿色激光治疗慢性中心性浆液性脉络膜视网膜病变的治疗效果及安全性分析

Going green - treatment outcome and safety profile of chronic central serous chorioretinopathy treated with subthreshold green laser.

作者信息

Khatri Anadi, Pradhan Eli, Singh Sweta, Rijal Roshija, Khatri Bal Kumar, Lamichhane Gyanendra, Kharel Muna

机构信息

Department of Retina, Lumbini Eye Institute, Lumbini, Nepal,

Department of Retina, Tilganga Institute of Ophthalmology, Kathmandu, Nepal.

出版信息

Clin Ophthalmol. 2018 Oct 5;12:1963-1971. doi: 10.2147/OPTH.S180663. eCollection 2018.

DOI:10.2147/OPTH.S180663
PMID:30323554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6178335/
Abstract

AIM

Subthreshold lasers have gained popularity in the treatment of chorioretinopathy central serous chorioretinopathy (CSCR) and yellow (577 nm) lasers have completely revolutionized the treatment. However, there is very little literature regarding the use of a more common and conventional - green (532 nm) subthreshold laser for the treatment of chronic CSCR. We report the use of green (532 nm) laser for the treatment of chronic CSCR and its outcome.

METHODS

Eyes with nonresolving CSCR were treated with green subthreshold laser and evaluated at the end of 5 months. Visual acuity, central macular thickness (CMT), and macular volume (MV) at baseline and at 5 months following treatment were evaluated.

RESULTS

Thirteen eyes with chronic CSCR were treated with green laser in SP-Mode™. The mean duration of CSCR was 7.64±3.77 months at the time of treatment. The median age of the patients was 41 (35-57) years. The baseline mean best-corrected visual acuity (BCVA) was 0.96 logMAR ± 0.17, with mean baseline CMT of 503.8 μm ± 181.9 and MV of 12.8 mm ± 3.81. The mean CMT at 5 months was 211 μm ± 31.7 and mean MV was 9.65 mm ± 0.60, correlating to a mean decrease of 292 μm ± 79 in CMT and mean decrease of 3.18 mm ± 1.87 in the MV from baseline (<0.05). The mean BCVA after treatment was 0.18 logMAR±0.09 (<0.05). Two cases of CSCR with pigment epithelial detachment (PED) also had complete resolution of both at 5 months.

CONCLUSION

Subthreshold green laser (532 nm) is a safe and effective modality for the treatment of chronic CSCR with very good and stable outcomes. It may also be beneficial in the treatment of PEDs.

摘要

目的

阈下激光在脉络膜视网膜病变(中心性浆液性脉络膜视网膜病变,CSCR)的治疗中已得到广泛应用,黄色(577纳米)激光彻底改变了该疾病的治疗方式。然而,关于使用更常见且传统的绿色(532纳米)阈下激光治疗慢性CSCR的文献却非常少。我们报告了使用绿色(532纳米)激光治疗慢性CSCR及其治疗结果。

方法

对CSCR未缓解的眼睛使用绿色阈下激光进行治疗,并在5个月末进行评估。评估了治疗前及治疗后5个月时的视力、中心黄斑厚度(CMT)和黄斑体积(MV)。

结果

13只患有慢性CSCR的眼睛采用SP-Mode™模式的绿色激光进行治疗。治疗时CSCR的平均病程为7.64±3.77个月。患者的中位年龄为41(35 - 57)岁。治疗前平均最佳矫正视力(BCVA)为0.96 logMAR±0.17,平均基线CMT为503.8微米±181.9,MV为12.8立方毫米±3.81。5个月时的平均CMT为211微米±31.7,平均MV为9.65立方毫米±0.60,与基线相比,CMT平均下降292微米±79,MV平均下降3.18立方毫米±1.87(<0.05)。治疗后的平均BCVA为0.18 logMAR±0.09(<0.05)。2例伴有色素上皮脱离(PED)的CSCR病例在5个月时PED也完全消退。

结论

阈下绿色激光(532纳米)是治疗慢性CSCR的一种安全有效的方法,具有非常好且稳定的治疗效果。它在PED的治疗中可能也有益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/2e92f692937c/opth-12-1963Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/980a7dadc2cd/opth-12-1963Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/f0ee59c6781a/opth-12-1963Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/3470bf422e3f/opth-12-1963Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/2e92f692937c/opth-12-1963Fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/980a7dadc2cd/opth-12-1963Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/f0ee59c6781a/opth-12-1963Fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/3470bf422e3f/opth-12-1963Fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37e5/6178335/2e92f692937c/opth-12-1963Fig4.jpg

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