Department of Pharmacology, B. J. Medical College, Ahmedabad, Gujarat, India.
Indian J Pharmacol. 2011 Sep;43(5):607-8. doi: 10.4103/0253-7613.84985.
A-24 year-old male was prescribed prednisolone (60 mg/day) for left sided facial palsy. After three days of therapy, the patient complained of black spots in his vision in right eye. Fluorescein angiography of right eye showed evidence of central serous retinopathy (CSR). Prednisolone dose was withdrawn gradually and the patient improved within a week. There were no other systemic or ophthalmic diseases reported by the patient, which could have caused this condition. An improvement after dechallenge confirmed steroid-induced CSR. Recurrent CSR is known to cause permanent loss of vision. Hence, awareness regarding this adverse drug reaction (ADR) with steroids and its reporting can minimize this complication and help in better patient management.
一位 24 岁男性因左侧面部瘫痪被开处泼尼松龙（60mg/天）治疗。治疗三天后，患者主诉右眼出现黑影。右眼荧光素血管造影显示为中心性浆液性脉络膜视网膜病变（CSR）。逐渐减少泼尼松龙剂量，患者在一周内好转。患者无其他可能导致这种情况的全身或眼部疾病。停药后改善证实了类固醇诱导的 CSR。已知复发性 CSR 可导致永久性视力丧失。因此，了解类固醇的这种药物不良反应（ADR）及其报告可以最大限度地减少这种并发症，并有助于更好地管理患者。
