Rincic Antulov Marijana, Båtevik Runar B
Department of Surgery, Sydvestjysk Sygehus, Esbjerg, Denmark.
Case Rep Gastroenterol. 2018 Sep 18;12(3):556-558. doi: 10.1159/000486952. eCollection 2018 Sep-Dec.
Angiotensin-converting enzyme inhibitors (ACEI) are widely used to treat hypertension and congestive heart failure. A rare side effect of ACEI therapy is angioedema, which in very rare cases may present as gastrointestinal angioedema (GA). A 45-year-old female presented with suddenly occurring diffuse abdominal pain. Imaging studies revealed small bowel wall edema. The patient had been on ACEI therapy for the last 6 months. The therapy was withdrawn, and the patient recovered quickly. There is no specific diagnostic test to confirm ACEI-induced GA, but symptoms usually regress completely after therapy discontinuation. An early diagnosis of ACEI-induced GA is important to avoid invasive diagnostic investigations and even laparotomy.
血管紧张素转换酶抑制剂（ACEI）被广泛用于治疗高血压和充血性心力衰竭。ACEI治疗的一种罕见副作用是血管性水肿，在极少数情况下可能表现为胃肠道血管性水肿（GA）。一名45岁女性出现突发弥漫性腹痛。影像学检查显示小肠壁水肿。该患者在过去6个月一直接受ACEI治疗。停用该治疗后，患者很快康复。目前尚无确诊ACEI诱发GA的特异性诊断测试，但症状通常在停药后完全消退。早期诊断ACEI诱发的GA对于避免进行侵入性诊断检查甚至剖腹手术很重要。
