Sarji K E, Levine J H, Nair R M, Sagel J, Colwell J A
J Clin Endocrinol Metab. 1977 Oct;45(4):853-6. doi: 10.1210/jcem-45-4-853.
The relationship between growth hormone and von Willebrand factor activity was studied in fasting plasma samples, nocturnal samples, and after intramuscular injection of growth hormone. A significant correlation was seen between the two levels in fasting samples. During sleep, peaks of growth hormone were associated with peaks of von Willebrand factor activity. A subject with isolated growth hormone deficiency had no peaks of either. Intramuscular injection of growth hormone produced a rise of von Willebrand factor activity in all subjects studied. These results indicate that there is a relationship between growth hormone and von Willebrand factor activity.
在空腹血浆样本、夜间样本以及肌肉注射生长激素后，对生长激素与血管性血友病因子活性之间的关系进行了研究。在空腹样本中，二者水平之间存在显著相关性。睡眠期间，生长激素峰值与血管性血友病因子活性峰值相关。一名孤立性生长激素缺乏的受试者二者均无峰值。对所有研究对象进行肌肉注射生长激素后，血管性血友病因子活性均升高。这些结果表明，生长激素与血管性血友病因子活性之间存在关联。
