Dick R, Platts A, Gilford J, Reddy K, Irving J D
Clin Radiol. 1987 Mar;38(2):175-8. doi: 10.1016/s0009-9260(87)80025-9.
Eighty-seven patients with malignant obstruction of the biliary tract from three centres and deemed unsuitable for surgery underwent insertion of the 'Carey-Coons' transhepatic endoprosthesis. It was successfully introduced in all, with early relief of cholestasis in 97%. The 30 day mortality rate was 11.5%, which is lower than reported in series using different endoprostheses. Two fifths of patients had complications, especially cholangitis. Despite its ease of insertion the design of the endoprosthesis may be related to the high incidence of cholangitis and to formation of biliary sludge and occlusion found in follow up. Although the anchoring threads prevented migration, they may have played a role in infection at the skin entry site in four patients and in tumour seeding to the skin in a further two. Still further improvements in endoprosthesis design are desirable.
来自三个中心的87例恶性胆道梗阻患者被认为不适合手术,接受了“凯里 - 孔斯”经肝内支架植入术。所有患者均成功植入,97%的患者胆汁淤积得到早期缓解。30天死亡率为11.5%,低于使用不同内支架的系列报道。五分之二的患者出现并发症,尤其是胆管炎。尽管该内支架易于植入,但其设计可能与胆管炎的高发生率以及随访中发现的胆泥形成和堵塞有关。虽然固定线防止了移位,但它们可能在4例患者的皮肤入口处感染以及另外2例患者的肿瘤种植到皮肤中起了作用。内支架设计仍需进一步改进。