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利用傅里叶变换轮廓术对健康眼睛的角巩膜几何结构进行表征。

Characterization of Corneoscleral Geometry Using Fourier Transform Profilometry in the Healthy Eye.

作者信息

Piñero David P, Martínez-Abad Antonio, Soto-Negro Roberto, Ariza-Gracia Miguel Angel, Carracedo Gonzalo

机构信息

Group of Optics and Visual Perception (D.P.P., A.M.-A.), Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain; Department of Ophthalmology (OFTALMAR) (D.P.P., R.S.-N.), Vithas Medimar International Hospital, Alicante, Spain; Aragón Institute for Engineering Research (i3A) (M.A.A.-G.), University of Zaragoza, Zaragoza, Spain; and Department of Optics II (G.C.), University Complutense of Madrid, Madrid, Spain.

出版信息

Eye Contact Lens. 2019 May;45(3):201-207. doi: 10.1097/ICL.0000000000000560.

Abstract

OBJECTIVE

To characterize peculiarities of the corneoscleral geometry in healthy eyes.

METHODS

This is a prospective case series including 88 healthy eyes of 88 patients with an age ranging from 21 to 73 years. A complete ocular examination was performed with emphasis on the analysis of the corneoscleral topographic profile with the Fourier transform profilometer Eye Surface Profiler (Eaglet-Eye BV, Houten, the Netherlands). The distribution of different topographic parameters was evaluated, as well as the correlations between corneal and scleroconjunctival parameters.

RESULTS

Mean values of 8.64±0.37 (range, 7.81-9.50 mm), 6.06±0.52 (4.88-7.63 mm) and 11.93±1.32 mm (8.17-15.89 mm) were obtained for inner, limbal, and outer best-fit sphere, respectively. Mean values of 8.54±0.38 (7.86-9.66 mm) and 13.35±1.29 mm (11.05-17.31 mm) were obtained for mean corneal and scleral radius, respectively. Regarding tangent angles at limbus, mean values of 35.31±6.55°, 38.76±5.90°, 32.75±7.04°, and 25.91±8.99° were obtained for nasal, temporal, superior, and inferior angles, respectively. Mean difference between temporal and nasal sagittal heights increased from -1.48±120.70 μm for a chord of 11 mm to 73.53±236.55 μm for a chord of 14 mm. A weak but statistically significant correlation was found between corneal and scleral radii (r=0.325, P=0.004). The maximum sagittal height for a diameter of 12 mm was significantly correlated with flattest keratometry, astigmatism, corneal diameter, and corneal eccentricity (R: 0.77, P<0.001).

CONCLUSIONS

The scleroconjunctival surface in the healthy eye presents some level of nasotemporal asymmetry that is higher with increasing diameters of analysis.

摘要

目的

描述健康眼的角巩膜几何特征。

方法

这是一个前瞻性病例系列研究,纳入了88例年龄在21至73岁之间的患者的88只健康眼。进行了全面的眼部检查,重点是使用傅里叶变换轮廓仪眼表面轮廓仪(Eaglet-Eye BV,荷兰豪滕)分析角巩膜地形轮廓。评估了不同地形参数的分布,以及角膜和巩膜结膜参数之间的相关性。

结果

内、角膜缘和外最佳拟合球的平均值分别为8.64±0.37(范围7.81 - 9.50毫米)、6.06±0.52(4.88 - 7.63毫米)和11.93±1.32毫米(8.17 - 15.89毫米)。平均角膜半径和巩膜半径的平均值分别为8.54±0.38(7.86 - 9.66毫米)和13.35±1.29毫米(11.05 - 17.31毫米)。关于角膜缘的切线角,鼻侧、颞侧、上方和下方角的平均值分别为35.31±6.55°、38.76±5.90°、32.75±7.04°和25.91±8.99°。颞侧和鼻侧矢状高度的平均差异从11毫米弦长时的-1.48±120.70微米增加到14毫米弦长时的73.53±236.55微米。角膜半径和巩膜半径之间存在微弱但具有统计学意义的相关性(r = 0.325,P = 0.004)。12毫米直径的最大矢状高度与最平坦角膜曲率、散光、角膜直径和角膜偏心度显著相关(R:0.77,P < 0.001)。

结论

健康眼中的巩膜结膜表面存在一定程度的鼻颞侧不对称,且随着分析直径的增加而增大。

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