Bataille Laurent, Molina-Martin Ainhoa, Piñero David P
Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain.
Group of Optics and Visual Perception. Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain; Department of Ophthalmology, Vithas Medimar International Hospital, Alicante, Spain.
Cont Lens Anterior Eye. 2021 Oct;44(5):101382. doi: 10.1016/j.clae.2020.11.002. Epub 2020 Nov 23.
To evaluate the intrasession repeatability of corneal, limbal and scleral measurements obtained by an experienced operator with a Fourier transform profilometer in healthy eyes.
Prospective, single-center study including 35 eyes of 35 participants with ages ranging from 13 to 52 years. All patients underwent three consecutive corneoscleral topographic evaluations with the Eye Surface Profiler (ESP) system (Eaglet Eye b.v.). Intrasession repeatability was analyzed for different geometric and sagittal height variables using the following parameters: the within-subject standard deviation (S) of the three consecutive measurements, intrasubject precision (1.96 × S), coefficient of variation (CV) and the intraclass correlation coefficient (ICC).
Inner best fit sphere (BFS) showed good repeatability, with ICC of 0.844. Higher variability was observed for the repeated measurements of limbus and outer BFS, with ICCs of 0.636 and 0.739, respectively. For mean corneal and scleral radius, ICCs were 0.933 and 0.888, respectively. The repeatability of all sagittal height data was good for all chords evaluated (11-15 mm), with Sw values from 0.02 to 0.11 mm, and ICCs from 0.568 to 0.909. A significant positive correlation was found between the magnitude of temporal-nasal sagittal height difference for all measured chords and its S associated.
The ESP system can provide consistent measurements of sagittal height data for different chord diameters as well as for mean corneal and scleral radius in healthy eyes. Best fit approaches for limbal and scleral areas were less repeatable, although within a clinically acceptable range.
评估经验丰富的操作人员使用傅里叶变换轮廓仪在健康眼睛中获得的角膜、角膜缘和巩膜测量值的测量间期重复性。
前瞻性单中心研究，纳入35名年龄在13至52岁之间的参与者的35只眼睛。所有患者使用眼表轮廓仪（ESP）系统（鹰眼光电有限公司）连续进行三次角膜巩膜地形图评估。使用以下参数分析不同几何和矢状高度变量的测量间期重复性：连续三次测量的受试者内标准差（S）、受试者内精密度（1.96×S）、变异系数（CV）和组内相关系数（ICC）。
内部最佳拟合球（BFS）显示出良好的重复性，ICC为0.844。角膜缘和外部BFS的重复测量显示出较高的变异性，ICC分别为0.636和0.739。对于平均角膜和巩膜半径，ICC分别为0.933和0.888。所有矢状高度数据对于所有评估的弦（11 - 15毫米）重复性良好，Sw值在0.02至0.11毫米之间，ICC在0.568至0.909之间。在所有测量弦的颞侧 - 鼻侧矢状高度差的大小与其相关的S之间发现显著正相关。
ESP系统可以为健康眼睛中不同弦直径以及平均角膜和巩膜半径的矢状高度数据提供一致的测量。角膜缘和巩膜区域的最佳拟合方法重复性较差，尽管在临床可接受范围内。
