Herzmann C
Aktuelle Gerontol. 1978 Sep;8(9):481-5.
All antidepressants now used have a cardiotropic, for some instances also cardiotoxic effect. This quinidine-like effect prolongs the QT-interval of ECG and can induce reentry and ventricular fibrillation. When quinidine and antidepressants are combined in the same patient the risk of such cardiac complications increases.
目前使用的所有抗抑郁药都有心脏效应,在某些情况下还具有心脏毒性作用。这种类似奎尼丁的效应会延长心电图的QT间期,并可诱发折返和心室颤动。当奎尼丁和抗抑郁药在同一患者体内联合使用时,发生此类心脏并发症的风险会增加。