全细胞DNA限制性内切酶图谱在艰难梭菌所致腹泻流行病学中的应用。
Application of whole-cell DNA restriction endonuclease profiles to the epidemiology of Clostridium difficile-induced diarrhea.
作者信息
Kuijper E J, Oudbier J H, Stuifbergen W N, Jansz A, Zanen H C
出版信息
J Clin Microbiol. 1987 Apr;25(4):751-3. doi: 10.1128/jcm.25.4.751-753.1987.
Abstract
Two patients in one hospital room acquired pseudomembranous colitis, one shortly after the other. The DNA restriction patterns of isolates from the patients and of four isolates from the environment were indistinguishable from one another and differed from isolates of other patients. Restriction endonuclease digest analysis appears to be a useful method for studying the epidemiology of Clostridium difficile.
摘要
同一病房的两名患者相继患上了伪膜性结肠炎。从这两名患者身上分离出的菌株以及从环境中分离出的四株菌株的DNA限制性图谱彼此无法区分，且与其他患者的菌株不同。限制性内切酶消化分析似乎是研究艰难梭菌流行病学的一种有用方法。
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