袖状胃切除术使一名病态肥胖的日本患者的缓慢进展型1型糖尿病得到缓解。
Sleeve Gastrectomy Induced Remission of Slowly Progressive Type 1 Diabetes in a Morbidly Obese Japanese Patient.
作者信息
Hironaka Jun-Ya, Kitahama Seiichi, Sato Hiroyuki, Inoue Maki, Takahashi Tetsuya, Tamori Yoshikazu
机构信息
Division of Diabetes and Endocrinology, Department of Internal Medicine, Chibune General Hospital, Japan.
Department of Bariatric and Metabolic Surgery, Chibune General Hospital, Japan.
出版信息
Intern Med. 2019 Mar 1;58(5):675-678. doi: 10.2169/internalmedicine.1217-18. Epub 2018 Oct 17.
The effects of bariatric/metabolic surgery on glycemic control in obese type 1 diabetic patients are controversial. We herein report a case of a morbidly obese 35-year-old woman who completely recovered from slowly progressive type 1 diabetes (SPIDDM) following laparoscopic sleeve gastrectomy. Preoperatively, her body mass index (BMI) was 49.8 kg/m and hemoglobin A1c was 5.7% with intensive insulin therapy. Six months after bariatric/metabolic surgery, her BMI decreased to 33.2 kg/m and her glycemic control was normal despite the discontinuation of all diabetic medicine. This case demonstrates the usefulness of bariatric/metabolic surgery for achieving glycemic control in morbidly obese patients with SPIDDM in Japan.
减肥/代谢手术对肥胖的1型糖尿病患者血糖控制的影响存在争议。我们在此报告一例35岁病态肥胖女性病例，该患者在腹腔镜袖状胃切除术后从缓慢进展性1型糖尿病（SPIDDM）中完全康复。术前，她的体重指数（BMI）为49.8kg/m，强化胰岛素治疗下糖化血红蛋白为5.7%。减肥/代谢手术后6个月，她的BMI降至33.2kg/m，尽管停用了所有糖尿病药物，但其血糖控制仍正常。该病例证明了减肥/代谢手术在日本对病态肥胖的SPIDDM患者实现血糖控制的有效性。
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