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腹腔镜袖状胃切除术:不仅仅是一种限制性减肥手术?

Laparoscopic sleeve gastrectomy: More than a restrictive bariatric surgery procedure?

作者信息

Benaiges David, Más-Lorenzo Antonio, Goday Albert, Ramon José M, Chillarón Juan J, Pedro-Botet Juan, Flores-Le Roux Juana A

机构信息

David Benaiges, Antonio Más-Lorenzo, Albert Goday, Juan J Chillarón, Juan Pedro-Botet, Juana A Flores-Le Roux, Department of Endocrinology and Nutrition, Hospital del Mar, E-08003 Barcelona, Spain.

出版信息

World J Gastroenterol. 2015 Nov 7;21(41):11804-14. doi: 10.3748/wjg.v21.i41.11804.

Abstract

Sleeve gastrectomy (SG) is a restrictive bariatric surgery technique that was first used as part of restrictive horizontal gastrectomy in the original Scopinaro type biliopancreatic diversion. Its good results as a single technique have led to a rise in its use, and it is currently the second most performed technique worldwide. SG achieves clearly better results than other restrictive techniques and is comparable in some aspects to the Roux-en-Y gastric bypass, the current gold standard in bariatric surgery. These benefits have been associated with different pathophysiologic mechanisms unrelated to weight loss such as increased gastric emptying and intestinal transit, and activation of hormonal mechanisms such as increased GLP-1 hormone and decreased ghrelin. The aim of this review was to highlight the salient aspects of SG regarding its historical evolution, pathophysiologic mechanisms, main results, clinical applications and perioperative complications.

摘要

袖状胃切除术(SG)是一种限制性减肥手术技术,最初作为原始斯科皮纳罗式胆胰转流术中限制性水平胃切除术的一部分使用。其作为单一技术取得的良好效果导致其应用增加,目前它是全球第二常用的技术。SG比其他限制性技术取得的效果明显更好,在某些方面与减肥手术的当前金标准——Roux-en-Y胃旁路术相当。这些益处与体重减轻无关的不同病理生理机制有关,如胃排空和肠道转运增加,以及激素机制的激活,如胰高血糖素样肽-1(GLP-1)激素增加和胃饥饿素减少。本综述的目的是强调SG在其历史演变、病理生理机制、主要结果、临床应用和围手术期并发症方面的突出特点。

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